Systemic Administration of a Brain Permeable Cdk5 Inhibitor Alters Neurobehavior
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DOI: 10.3389/fphar.2022.863762
Abstract: Cyclin-dependent kinase 5 (Cdk5) is a crucial regulator of neuronal signal transduction. Cdk5 activity is implicated in various neuropsychiatric and neurodegenerative conditions such as stress, anxiety, depression, addiction, Alzheimer’s disease, and Parkinson’s disease. While constitutive… read more here.
Keywords: cdk5 inhibitor; systemic administration; brain; administration brain ... See more keywords