Quantitative structure-toxicity relationship model for acute toxicity of organophosphates via multiple administration routes in rats and mice.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of hazardous materials"
DOI: 10.1016/j.jhazmat.2020.123724
Abstract: Organophosphates (OPs) are highly toxic compounds, with widespread application in agricultural and chemical industries, whose introduction into the environment poses serious hazards to humans and ecological systems. To assess and ultimately mitigate these hazards, this… read more here.
Keywords: toxicity; administration routes; acute toxicity; quantitative structure ... See more keywords
Administration Routes of Polyethylenimine-Coated PLGA Nanoparticles Encapsulating Angelica Sinensis Polysaccharide Vaccine Delivery System Affect Immune Responses.
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DOI: 10.1021/acs.molpharmaceut.1c00090
Abstract: Nanoparticle vaccine delivery systems have been emerging strategies for inducing potent immune responses to prevent and treat infectious diseases and cancers. The properties of nanoparticle vaccine delivery systems, such as nanoparticle size, surface charge, and… read more here.
Keywords: administration routes; delivery; immune responses; vaccine delivery ... See more keywords
Administration Routes as Modulators of the Intrahepatic Distribution and Anti-Anemic Activity of Salicylic Acid/Fe3O4 Nanoparticles
Sign Up to like & getrecommendations! Published in 2022 at "Biomedicines"
DOI: 10.3390/biomedicines10051213
Abstract: The liver is a key organ in the pharmacokinetics of iron oxide nanoparticles (IONPs). This paper examined how the intravenous (IV) or intragastric (IG) route of administration influenced the intrahepatic distribution or therapeutic effects of… read more here.
Keywords: administration routes; salicylic acid; administration; intrahepatic distribution ... See more keywords
Recent Advances in the Polish Research on Polysaccharide-Based Nanoparticles in the Context of Various Administration Routes
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DOI: 10.3390/biomedicines11051307
Abstract: Polysaccharides are the most abundant polymers in nature. They exhibit robust biocompatibility, reliable non-toxicity, and biodegradable character; thus, they are employed in multiple biomedical applications. The presence of chemically accessible functional groups on the backbone… read more here.
Keywords: administration; research; administration routes; polysaccharide based ... See more keywords
Formulation Strategies of Nanosuspensions for Various Administration Routes
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DOI: 10.3390/pharmaceutics15051520
Abstract: Nanosuspensions (NSs), which are nanosized colloidal particle systems, have recently become one of the most interesting substances in nanopharmaceuticals. NSs have high commercial potential because they provide the enhanced solubility and dissolution of low-water-soluble drugs… read more here.
Keywords: administration; administration routes; formulation strategies; strategies nanosuspensions ... See more keywords