Effects of mitomycin-C and 5-fluorouracil on ocular adnexal sebaceous carcinoma cells.
Sign Up to like & getrecommendations! Published in 2022 at "American journal of ophthalmology"
DOI: 10.1016/j.ajo.2021.12.016
Abstract: PURPOSE To investigate the effects of mitomycin-C (MMC) and 5-fluorouracil (5-FU) on the viability, proliferation, and migratory capacity of cultured ocular adnexal sebaceous carcinoma (SC) cells. DESIGN Laboratory investigation. METHODS Human SC cell lines (Bascom… read more here.
Keywords: sebaceous carcinoma; viability; adnexal sebaceous; effects mitomycin ... See more keywords
Whole-exome sequencing for ocular adnexal sebaceous carcinoma suggests PCDH15 as a novel mutation associated with metastasis
Sign Up to like & getrecommendations! Published in 2020 at "Modern Pathology"
DOI: 10.1038/s41379-020-0454-y
Abstract: Ocular adnexal sebaceous carcinoma (OASeC) is an aggressive eyelid carcinoma. Analysis of molecular-genetic drivers of this disease could reveal new prognostic markers and actionable targets for treatment. To identify somatically acquired genomic mutations in OASeC… read more here.
Keywords: carcinoma; associated metastasis; metastasis; ocular adnexal ... See more keywords
Distinct Biological Types of Ocular Adnexal Sebaceous Carcinoma: HPV-Driven and Virus-Negative Tumors Arise through Nonoverlapping Molecular-Genetic Alterations
Sign Up to like & getrecommendations! Published in 2018 at "Clinical Cancer Research"
DOI: 10.1158/1078-0432.ccr-18-1688
Abstract: Purpose: Ocular adnexal (OA) sebaceous carcinoma is an aggressive malignancy of the eyelid and ocular adnexa that frequently recurs and metastasizes, and effective therapies beyond surgical excision are lacking. There remains a critical need to… read more here.
Keywords: sebaceous carcinoma; tumors arise; molecular genetic; ocular adnexal ... See more keywords