Clinical Significance of DXA and HR-pQCT in Autosomal Dominant Osteopetrosis (ADO II)
Sign Up to like & getrecommendations! Published in 2017 at "Calcified Tissue International"
DOI: 10.1007/s00223-017-0332-x
Abstract: The main hallmark of high bone mass (HBM) disorders is increased bone mineral density, potentially visible in conventional radiographs and quantifiable by other radiographic methods. While one of the most common forms of HBM is… read more here.
Keywords: hbm; dominant osteopetrosis; ado; autosomal dominant ... See more keywords
CD73 Downregulation Decreases In Vitro and In Vivo Glioblastoma Growth
Sign Up to like & getrecommendations! Published in 2018 at "Molecular Neurobiology"
DOI: 10.1007/s12035-018-1240-4
Abstract: AbstractGlioblastoma is the worst and most common primary brain tumor. Here, we demonstrated the role of CD73, an enzyme responsible for adenosine (ADO) production, in glioblastoma progression. ADO increased glioma cell viability via A1 receptor… read more here.
Keywords: ado; glioma; glioblastoma; cd73 downregulation ... See more keywords
Shared and distinct white matter abnormalities in adolescent-onset schizophrenia and adolescent-onset psychotic bipolar disorder.
Sign Up to like & getrecommendations! Published in 2022 at "Psychological medicine"
DOI: 10.1017/s003329172200160x
Abstract: BACKGROUND While adolescent-onset schizophrenia (ADO-SCZ) and adolescent-onset bipolar disorder with psychosis (psychotic ADO-BPD) present a more severe clinical course than their adult forms, their pathophysiology is poorly understood. Here, we study potentially state- and trait-related… read more here.
Keywords: white matter; matter abnormalities; adolescent onset; ado ... See more keywords
Light-Activated Electron Transfer and Turnover in Ru-Modified Aldehyde Deformylating Oxygenases.
Sign Up to like & getrecommendations! Published in 2018 at "Inorganic chemistry"
DOI: 10.1021/acs.inorgchem.8b00673
Abstract: Conversion of biological molecules into fuels or other useful chemicals is an ongoing chemical challenge. One class of enzymes that has received attention for such applications is aldehyde deformylating oxygenase (ADO) enzymes. These enzymes convert… read more here.
Keywords: ado; turnover; electron transfer; aldehyde deformylating ... See more keywords
Adenosine Awakens Metabolism to Enhance Growth-Independent Killing of Tolerant and Persister Bacteria across Multiple Classes of Antibiotics
Sign Up to like & getrecommendations! Published in 2022 at "mBio"
DOI: 10.1128/mbio.00480-22
Abstract: Antibiotic tolerance, which is a hallmark of persister bacteria, contributes to treatment-refractory infections and the emergence of heritable antimicrobial resistance. Drugs that reverse tolerance and persistence may become part of the arsenal to combat antimicrobial… read more here.
Keywords: antibiotic tolerance; growth; persister bacteria; resistance ... See more keywords
GP23 Percutaneous closure of patent ductus arteriosus: single center experience
Sign Up to like & getrecommendations! Published in 2019 at "Archives of Disease in Childhood"
DOI: 10.1136/archdischild-2019-epa.90
Abstract: Aim In this study, we aimed to evaluate our clinical experiences in the percutaneous closure of patent ductus arteriosus (PDA) in the pediatric population with our early and late results. Method A total of 156… read more here.
Keywords: ductus; ado; closure; percutaneous closure ... See more keywords
Abstract 2640: Small-molecule inhibitors of CD73, CD39 and A2aR: Three anti-cancer targets in the ATP/adenosine signaling pathway
Sign Up to like & getrecommendations! Published in 2017 at "Cancer Research"
DOI: 10.1158/1538-7445.am2017-2640
Abstract: INTRODUCTION: In the tumor micro-environment (TME) Adenosine (ADO) dampens the immune response towards cancer cells by inhibiting the cytotoxic activity of effector cells and promoting the proliferation of immunosuppressive cells. Extracellular ADO is generated by… read more here.
Keywords: tumor; ado; small molecule; inhibition ... See more keywords
The stability of the ADO score among UK COPD patients from The Health Improvement Network
Sign Up to like & getrecommendations! Published in 2020 at "ERJ Open Research"
DOI: 10.1183/23120541.00196-2019
Abstract: The ADO (age, dyspnoea, airflow obstruction) score predicts 3-year overall mortality among chronic obstructive pulmonary disease (COPD) patients. Information on the changes in COPD prognostic scores is sparse and it is unclear if the ADO… read more here.
Keywords: ado score; ado; copd patients; improvement network ... See more keywords
Família, maternidade, escravidão e resgate forçado na Martinica (1845-1847)
Sign Up to like & getrecommendations! Published in 2023 at "Tempo"
DOI: 10.1590/tem-1980-542x2023v290103
Abstract: Resumo: Nos anos finais da escravidão no mundo Atlântico francês, a política colonial passou por mudanças que afetaram o domínio senhorial. Sob a Lei Mackau, regulamentaram-se os direitos das pessoas escravizadas ao pecúlio e à… read more here.
Keywords: ado; martinica; maternidade escravid; resgate ado ... See more keywords
Autosomal dominant osteopetrosis.
Sign Up to like & getrecommendations! Published in 2023 at "Bone"
DOI: 10.2139/ssrn.4290887
Abstract: Autosomal dominant osteopetrosis (ADO) is the most common form of osteopetrosis. ADO is characterized by generalized osteosclerosis along with characteristic radiographic features such as a "bone-in-bone" appearance of long bones and sclerosis of the superior… read more here.
Keywords: osteopetrosis; disease; autosomal dominant; ado ... See more keywords
Synergy of Venetoclax and 8-Chloro-Adenosine in AML: The Interplay of rRNA Inhibition and Fatty Acid Metabolism
Sign Up to like & getrecommendations! Published in 2022 at "Cancers"
DOI: 10.3390/cancers14061446
Abstract: Simple Summary Treatment failures of acute myeloid leukemia (AML) have been attributed to the persistence of leukemia stem cells (LSCs), which are refractory to conventional treatments. Venetoclax (VEN), currently FDA-approved in combination with low-dose cytarabine… read more here.
Keywords: aml; ado; chloro adenosine; ven ado ... See more keywords