Hippocampal amino‐3‐hydroxy‐5‐methyl‐4‐isoxazolepropionic acid GluA1 (AMPA GluA1) receptor subunit involves in learning and memory improvement following treatment with Centella asiatica extract in adolescent rats
Sign Up to like & getrecommendations! Published in 2018 at "Brain and Behavior"
DOI: 10.1002/brb3.1093
Abstract: Centella asiatica is an herbal plant that contains phytochemicals that are widely believed to have positive effects on cognitive function. The adolescent stage is a critical development period for the maturation of brain processes that… read more here.
Keywords: glua1; asiatica; learning memory; asiatica extract ... See more keywords
From adolescent to elder rats: Motivation for palatable food and cannabinoids receptors
Sign Up to like & getrecommendations! Published in 2017 at "Developmental Neurobiology"
DOI: 10.1002/dneu.22472
Abstract: To analyze motivation, food self‐administration and decision‐making were evaluated in adolescent, adult, and aged rats. Subjects were trained to press a lever (fixed ratio, FR1 and FR5) in an operant chamber, to obtain chocolate flavor… read more here.
Keywords: aged rats; adolescent rats; adult aged; motivation palatable ... See more keywords
Binge drinking in male adolescent rats and its relationship to persistent behavioral impairments and elevated proinflammatory/proapoptotic proteins in the cerebellum
Sign Up to like & getrecommendations! Published in 2020 at "Psychopharmacology"
DOI: 10.1007/s00213-020-05458-3
Abstract: Rationale To demonstrate that repeated episodes of binge drinking during the adolescent period can lead to long-term deficits in motor function and memory in adulthood, and increase proteins in the brain involved with inflammation and… read more here.
Keywords: binge drinking; male adolescent; drinking male; rats relationship ... See more keywords
Early-life lipopolysaccharide exposure potentiates forebrain expression of NLRP3 inflammasome proteins and anxiety-like behavior in adolescent rats
Sign Up to like & getrecommendations! Published in 2017 at "Brain Research"
DOI: 10.1016/j.brainres.2017.06.014
Abstract: BACKGROUND Neonatal inflammation may affect brain development and lead to cognitive and emotional deficits at adolescence and adulthood. The nucleotide binding and oligomerization domain-like receptor family pyrin domain-containing 3 (NLRP3) is the core component of… read more here.
Keywords: expression nlrp3; early life; like behavior; adolescent rats ... See more keywords
Dose-dependent opposite effects of nortriptyline on affective-like behavior in adolescent rats: Comparison with adult rats.
Sign Up to like & getrecommendations! Published in 2021 at "European journal of pharmacology"
DOI: 10.1016/j.ejphar.2021.174465
Abstract: Antidepressant drugs elicit different behavioral and neurochemical responses with age. In fact, the use of antidepressants during adolescence is associated with an increased risk of suicidal thinking, being the best pharmacological treatment during this critical… read more here.
Keywords: adult; effects nortriptyline; like behavior; adult rats ... See more keywords
Previous Early-life Stress Modifies Acute Corticosterone-induced Synaptic Plasticity in the Medial Prefrontal Cortex of Adolescent Rats
Sign Up to like & getrecommendations! Published in 2018 at "Neuroscience"
DOI: 10.1016/j.neuroscience.2018.03.038
Abstract: Stress can either strengthen coping strategies or enhance the risk of depression and anxiety. Synaptic plasticity is one of the key brain functions that can be affected by stress. We have previously shown that early-life… read more here.
Keywords: life stress; early life; stress; adolescent rats ... See more keywords
Biological implications of selenium in adolescent rats exposed to binge drinking: Oxidative, immunologic and apoptotic balance
Sign Up to like & getrecommendations! Published in 2017 at "Toxicology and Applied Pharmacology"
DOI: 10.1016/j.taap.2017.05.037
Abstract: &NA; Alcohol intermittent binge drinking (BD) during adolescence decreases the levels of selenium (Se), a trace element that plays a key biological role against oxidative damage in hepatocytes through different selenoproteins such as the antioxidant… read more here.
Keywords: supplementation; binge drinking; adolescent rats; expression ... See more keywords
Minocycline prevents neuronal hyperexcitability and neuroinflammation in medial prefrontal cortex, as well as memory impairment caused by repeated toluene inhalation in adolescent rats.
Sign Up to like & getrecommendations! Published in 2020 at "Toxicology and applied pharmacology"
DOI: 10.1016/j.taap.2020.114980
Abstract: Toluene can be intentionally misused by adolescents to experience psychoactive effects. Toluene has a complex mechanism of action and broad behavioral effects, among which memory impairment is reported consistently. We have previously reported that repeated… read more here.
Keywords: hyperexcitability; toluene inhalation; memory impairment; repeated toluene ... See more keywords
Neurocan regulates vulnerability to stress and the anti-depressant effect of ketamine in adolescent rats
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DOI: 10.1038/s41380-022-01495-w
Abstract: Depression is more prevalent among adolescents than adults, but the underlying mechanisms remain largely unknown. Using a subthreshold chronic stress model, here we show that developmentally regulated expressions of the perineuronal nets (PNNs), and one… read more here.
Keywords: anti depressant; effect ketamine; stress; depressant effect ... See more keywords
Alteration of fear behaviors in sleep-deprived adolescent rats: increased fear expression and delayed fear extinction
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DOI: 10.1080/19768354.2021.1902854
Abstract: ABSTRACT Disruption of sleep due to acute or chronic stress can lead to changes in emotional memory processing. Sleep disturbances are highly prevalent in post-traumatic stress disorder (PTSD), but still, the contribution of sleep deprivation… read more here.
Keywords: fear; fear extinction; adolescent rats; fear expression ... See more keywords
Disruption of Rapid Eye Movement Sleep Homeostasis in Adolescent Rats after Neonatal Anesthesia
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DOI: 10.1097/aln.0000000000002660
Abstract: What We Already Know about This Topic Anesthesia in adult rodents has been associated with alterations in sleep architecture that persist up to 18 h after anesthesia What This Article Tells Us That Is New Anesthesia… read more here.
Keywords: rapid eye; movement sleep; adolescent rats; eye movement ... See more keywords