Early adolescent stress‐induced changes in prefrontal cortex miRNA‐135a and hippocampal miRNA‐16 in male rats
Sign Up to like & getrecommendations! Published in 2017 at "Developmental Psychobiology"
DOI: 10.1002/dev.21558
Abstract: Early-life stress increases susceptibility to post-traumatic stress disorders (PTSD), in which the dysfunction of 5-hydroxytryptamine plays an important role. miRNA-135a in the prefrontal cortex (PFC) and miRNA-16 in the hippocampus (HIP) are closely related to… read more here.
Keywords: adolescent stress; stress; expression; early adolescent ... See more keywords
Chronic adolescent stress sex-specifically alters central and peripheral neuro-immune reactivity in rats
Sign Up to like & getrecommendations! Published in 2019 at "Brain, Behavior, and Immunity"
DOI: 10.1016/j.bbi.2018.12.005
Abstract: Adversity during development is a reliable predictor of psychiatric disorders such as depression and anxiety which are increasingly recognized to have an immune component. We have previously demonstrated that chronic adolescent stress (CAS) in rats… read more here.
Keywords: immune reactivity; adolescent stress; cas; chronic adolescent ... See more keywords
Adolescent Stress Disrupts the Maturation of Anxiety-related Behaviors and Alters the Developmental Trajectory of the Prefrontal Cortex in a Sex- and Age-specific Manner
Sign Up to like & getrecommendations! Published in 2018 at "Neuroscience"
DOI: 10.1016/j.neuroscience.2018.08.030
Abstract: Adolescence is a window of vulnerability to environmental factors such as chronic stress that can disrupt brain development and cause long-lasting behavioral dysfunction, as seen in disorders like depression, anxiety, and schizophrenia. There are also… read more here.
Keywords: specific manner; adolescent stress; anxiety; adolescence ... See more keywords
Adolescent Stress as a Driving Factor for Schizophrenia Development-A Basic Science Perspective.
Sign Up to like & getrecommendations! Published in 2017 at "Schizophrenia bulletin"
DOI: 10.1093/schbul/sbx033
Abstract: Schizophrenia has been associated with heightened stress responsivity in adolescence that precedes onset of psychosis. We now report that multiple stressors during adolescence in normal rats leads to deficits in adults analogous to that seen… read more here.
Keywords: driving factor; schizophrenia; stress driving; adolescent stress ... See more keywords
Npas4 deficiency interacts with adolescent stress to disrupt prefrontal GABAergic maturation and adult cognitive flexibility
Sign Up to like & getrecommendations! Published in 2018 at "Genes"
DOI: 10.1111/gbb.12459
Abstract: Healthy cognitive and emotional functioning relies on a balance between excitatory and inhibitory neurotransmission in the prefrontal cortex (PFC). This balance is largely established during early postnatal and adolescent developmental periods by maturation of the… read more here.
Keywords: adolescent stress; stress; gabaergic maturation; npas4 deficiency ... See more keywords
Evaluation of the Factor Structure of the Adolescent Stress Questionnaire in Chinese Adolescents
Sign Up to like & getrecommendations! Published in 2018 at "Psychological Reports"
DOI: 10.1177/0033294118792686
Abstract: This study evaluated the psychometric properties of the Chinese version of Adolescent Stress Questionnaire (ASQ-CN) in a sample of Chinese middle school students (N = 420; 52.14% boys and 47.86% girls). Iterated principal factor analysis and multiple-group… read more here.
Keywords: adolescent stress; chinese adolescents; stress; factor structure ... See more keywords