Alteration of Tumor Metabolism by CD4+ T Cells Leads to TNF-α-Dependent Intensification of Oxidative Stress and Tumor Cell Death.
Sign Up to like & getrecommendations! Published in 2018 at "Cell metabolism"
DOI: 10.1016/j.cmet.2018.05.012
Abstract: The inhibitory effects of cancer on T cell metabolism have been well established, but the metabolic impact of immunotherapy on tumor cells is poorly understood. Here, we developed a CD4+ T cell-based adoptive immunotherapy protocol that was… read more here.
Keywords: tumor; metabolism; adoptive immunotherapy; cell ... See more keywords
Adoptive immunotherapy with autologous T cell infusions reduces opioid requirements in advanced cancer patients.
Sign Up to like & getrecommendations! Published in 2019 at "Pain"
DOI: 10.1097/j.pain.0000000000001702
Abstract: Relief of cancer-related pain remains challenging despite the availability of a range of opioid and non-opioid medications. Animal models demonstrate that T lymphocytes may mediate analgesia by producing endogenous opioids, but definitive clinical data are… read more here.
Keywords: immunotherapy autologous; cancer pain; adoptive immunotherapy; cancer ... See more keywords
Postoperative Adjuvant Therapy for Resectable Pancreatic Cancer With Gemcitabine and Adoptive Immunotherapy
Sign Up to like & getrecommendations! Published in 2017 at "Pancreas"
DOI: 10.1097/mpa.0000000000000880
Abstract: Objectives We previously described adoptive immunotherapy (AIT) with cytotoxic T lymphocytes (CTLs) stimulated by the mucin 1 (MUC1)–expressing human pancreatic cancer cell line YPK-1 (MUC1-CTLs) and demonstrated that MUC1-CTLs might prevent liver metastasis. In the… read more here.
Keywords: muc1 ctls; adoptive immunotherapy; pancreatic cancer; ctls ... See more keywords
Adoptive immunotherapy overcomes genetic susceptibility to bloodstream infections due to fc‐gamma receptor polymorphisms after liver transplantation
Sign Up to like & getrecommendations! Published in 2022 at "American Journal of Transplantation"
DOI: 10.1111/ajt.17113
Abstract: Single nucleotide polymorphisms (SNPs) in FCGR3A can predict the susceptibility of liver transplant (LT) recipients to bloodstream infections (BSI) and clinical outcomes following living‐donor LT (LDLT). Here, we retrospectively analyzed the relationship of adoptive immunotherapy… read more here.
Keywords: adoptive immunotherapy; bloodstream infections; bsi; liver ... See more keywords
Generation of induced pluripotent stem cell (iPSC) from NY‐ESO‐I‐specific cytotoxic T cells isolated from the melanoma patient with minor HLAs: The practical pilot study for the adoptive immunotherapy for melanoma using iPSC technology
Sign Up to like & getrecommendations! Published in 2022 at "Experimental Dermatology"
DOI: 10.1111/exd.14686
Abstract: Melanoma is one of the most severe skin cancers, derived from melanocytes. Among various therapies for melanoma, adoptive immunotherapy using tumor‐infiltrating lymphocytes/chimeric antigen receptor‐T cells (TCs) is advanced in recent years; however, the efficacy is… read more here.
Keywords: adoptive immunotherapy; cell; melanoma; immunotherapy ... See more keywords
The Combined Clinical Efficacy and Safety Analysis of Adoptive Immunotherapy with Radiotherapy and Chemotherapy in Non-Small-Cell Lung Cancer: Systematic Review and Meta-Analysis
Sign Up to like & getrecommendations! Published in 2022 at "Applied Bionics and Biomechanics"
DOI: 10.1155/2022/2731744
Abstract: Objective To explore the differential efficacy of chemoradiotherapy combined with adoptive immunotherapy and radiochemotherapy alone in patients with non-small-cell lung cancer (NSCLC). Methods Qualified randomized controlled trial (randomized controlled trial, RCT), or nonrandomized concurrent controlled… read more here.
Keywords: adoptive immunotherapy; non small; immunotherapy; small cell ... See more keywords
Abstract 3763: UCART22: allogenic adoptive immunotherapy of leukemia by targeting CD22 with CAR T-cells
Sign Up to like & getrecommendations! Published in 2017 at "Cancer Research"
DOI: 10.1158/1538-7445.am2017-3763
Abstract: Adoptive immunotherapy using autologous T-cells endowed with chimeric antigen receptors (CARs) has given rise to long-term durable remissions and remarkable objective response rates in patients with refractory leukemia, raising hopes that a wider application of… read more here.
Keywords: adoptive immunotherapy; cd22; targeting cd22; cd22 car ... See more keywords
CD56bright/CD16bright NK-cell adoptive immunotherapy in patients with concurrent CNS disease and relapsed or refractory (R/R) AML.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Clinical Oncology"
DOI: 10.1200/jco.2020.38.15_suppl.3025
Abstract: 3025Background: Patients (pts) with R/R AML and concurrent CNS disease rarely respond to chemotherapy and have a dismal prognosis. Adoptive immunotherapy (AI) with haploidentical ex vivo-activated/... read more here.
Keywords: concurrent cns; adoptive immunotherapy; cns disease; cd56bright cd16bright ... See more keywords
Adoptive immunotherapy shows encouraging benefit on non-small cell lung cancer: a systematic review and meta-analysis
Sign Up to like & getrecommendations! Published in 2017 at "Oncotarget"
DOI: 10.18632/oncotarget.19373
Abstract: Although adoptive immunotherapy (AIT) is a novel emerging target treatment for non-small cell lung cancer (NSCLC), its actual efficacy remains controversial. In this meta-analysis, we aimed to evaluate the efficacy of AIT for NSCLC. We… read more here.
Keywords: adoptive immunotherapy; analysis; year; non small ... See more keywords
Optimization of Culture Conditions for the Generation of Canine CD20-CAR-T Cells for Adoptive Immunotherapy
Sign Up to like & getrecommendations! Published in 2022 at "In Vivo"
DOI: 10.21873/invivo.12763
Abstract: Background/Aim: Chimeric antigen receptor (CAR) T cell therapy targeting CD20 has the potential to become a promising novel treatment for canine B cell lymphoid malignancy. However, the optimal approach for producing potent CAR-T cells with… read more here.
Keywords: adoptive immunotherapy; culture conditions; cd20 car; cells adoptive ... See more keywords
Current update of adoptive immunotherapy using cytokine-induced killer cells to eliminate malignant gliomas.
Sign Up to like & getrecommendations! Published in 2017 at "Immunotherapy"
DOI: 10.2217/imt-2017-0003
Abstract: The therapeutic outcome for those with malignant glioma is poor, even though diverse therapeutic modalities have been developed. Immunotherapy has emerged as a therapeutic approach for malignant gliomas, making it possible to selectively treat tumors… read more here.
Keywords: immunotherapy; malignant gliomas; adoptive immunotherapy; cytokine induced ... See more keywords