Evidence for persistent organochlorine pollutants in the human adrenal cortex
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Applied Toxicology"
DOI: 10.1002/jat.3460
Abstract: Environmental pollutants may act as endocrine disruptors in animals. Organochlorine pesticides (OCPs) and polychlorinated biphenyls (PCBs) enter the food chain and may accumulate in the fatty animal tissues, including adrenals. To our knowledge, no previous… read more here.
Keywords: persistent organochlorine; cortex; organochlorine pollutants; adrenal cortex ... See more keywords
Transcription analysis of the response of the porcine adrenal cortex to a single subclinical dose of lipopolysaccharide from Salmonella Enteritidis.
Sign Up to like & getrecommendations! Published in 2019 at "International journal of biological macromolecules"
DOI: 10.1016/j.ijbiomac.2019.09.067
Abstract: Lipopolysaccharide (LPS) is a bacterial endotoxin which can participate in the induction of inflammatory responses. LPS may also play a significant role in some neurodegenerative, oncological and metabolic disorders. The aim of the current study… read more here.
Keywords: adrenal cortex; salmonella enteritidis; subclinical dose; porcine adrenal ... See more keywords
Cell signaling pathways in the adrenal cortex: Links to stem/progenitor biology and neoplasia
Sign Up to like & getrecommendations! Published in 2017 at "Molecular and Cellular Endocrinology"
DOI: 10.1016/j.mce.2016.12.005
Abstract: The adrenal cortex is a dynamic tissue responsible for the synthesis of steroid hormones, including mineralocorticoids, glucocorticoids, and androgens in humans. Advances have been made in understanding the role of adrenocortical stem/progenitor cell populations in… read more here.
Keywords: homeostasis; signaling pathways; adrenal cortex; stem progenitor ... See more keywords
Regulation of the KCNJ5 gene by SF-1 in the adrenal cortex: Complete genomic organization and promoter function
Sign Up to like & getrecommendations! Published in 2020 at "Molecular and Cellular Endocrinology"
DOI: 10.1016/j.mce.2019.110657
Abstract: Activating mutations in the KCNJ5 gene are responsible for the significant number of aldosterone-producing adenomas. To elucidate the molecular mechanisms underlying KCNJ5 expression, we characterized the entire human KCNJ5 gene. The gene spanned approximately 29.8 kb… read more here.
Keywords: kcnj5 gene; adrenal cortex; regulation kcnj5; promoter ... See more keywords
Developmental mechanisms of adrenal cortex formation and their links with adult progenitor populations
Sign Up to like & getrecommendations! Published in 2021 at "Molecular and Cellular Endocrinology"
DOI: 10.1016/j.mce.2021.111172
Abstract: The adrenal cortex is the main steroid producing organ of the human body. Studies on adrenal tissue renewal have been neglected for many years, but recent intensified research has seen tremendous progress in our understanding… read more here.
Keywords: developmental mechanisms; mechanisms adrenal; cortex; adrenal cortex ... See more keywords
Corticosteroid Use and Periodontal Disease: A Systematic Review
Sign Up to like & getrecommendations! Published in 2020 at "European Journal of Dentistry"
DOI: 10.1055/s-0040-1713954
Abstract: Periodontitis affects the teeth supporting structures, such as periodontal tissues. We aimed to evaluate the association between periodontal disease and corticosteroid use. We searched in MEDLINE, Web of Sciences, SCOPUS, LILACS, and Cochrane databases, using… read more here.
Keywords: periodontal disease; adrenal cortex; corticosteroid use; disease ... See more keywords
The developmental origin and the specification of the adrenal cortex in humans and cynomolgus monkeys
Sign Up to like & getrecommendations! Published in 2022 at "Science Advances"
DOI: 10.1101/2022.01.19.477000
Abstract: Development of the adrenal cortex, a vital endocrine organ, originates in the adrenogonadal primordium, a common progenitor for both the adrenocortical and gonadal lineages in rodents. In contrast, we find that in humans and cynomolgus… read more here.
Keywords: adrenal cortex; humans cynomolgus; cynomolgus monkeys; specification adrenal ... See more keywords
Effect of Inactivation of Mst1 and Mst2 in the Mouse Adrenal Cortex
Sign Up to like & getrecommendations! Published in 2022 at "Journal of the Endocrine Society"
DOI: 10.1210/jendso/bvac143
Abstract: Abstract Recent conditional knockout of core components of the Hippo signaling pathway in the adrenal gland of mice has demonstrated that this pathway must be tightly regulated to ensure proper development and maintenance of the… read more here.
Keywords: adrenal cortex; mouse adrenal; mst1; mst2 ... See more keywords
Transgenic Mouse Models to Study the Development and Maintenance of the Adrenal Cortex
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms232214388
Abstract: The cortex of the adrenal gland is organized into concentric zones that produce distinct steroid hormones essential for body homeostasis in mammals. Mechanisms leading to the development, zonation and maintenance of the adrenal cortex are… read more here.
Keywords: adrenal cortex; development; mouse; maintenance adrenal ... See more keywords
Characterizing and Quenching Autofluorescence in Fixed Mouse Adrenal Cortex Tissue
Sign Up to like & getrecommendations! Published in 2023 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms24043432
Abstract: Tissue autofluorescence of fixed tissue sections is a major concern of fluorescence microscopy. The adrenal cortex emits intense intrinsic fluorescence that interferes with signals from fluorescent labels, resulting in poor-quality images and complicating data analysis.… read more here.
Keywords: adrenal cortex; microscopy; autofluorescence; autofluorescence fixed ... See more keywords
Stress-induced changes in the aged-rat adrenal cortex. Histological and histomorphometric study.
Sign Up to like & getrecommendations! Published in 2018 at "Folia morphologica"
DOI: 10.5603/fm.a2018.0035
Abstract: BACKGROUND Stress exposure exerts direct effects on the morphology and functionality of the adrenal cortex. In addition, ageing effects growth, differentiation, apoptosis and cellularity of the cortex. The missing data is the combined effect of… read more here.
Keywords: adrenal cortex; group; study; stress ... See more keywords