The Antiarrhythmic and Hypotensive Effects of S-61 and S-73, the Pyrrolidin-2-one Derivatives with α1-Adrenolytic Properties
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DOI: 10.3390/ijms231810381
Abstract: Heart rhythm abnormalities are a cause of many deaths worldwide. Unfortunately, the available antiarrhythmic drugs show limited efficacy and proarrhythmic potential. Thus, efforts should be made to search for new, more effective, and safer pharmacotherapies.… read more here.
Keywords: adrenolytic properties; hypotensive effects; one derivatives; induced arrhythmia ... See more keywords
HBK-10, A Compound with α1-Adrenolytic Properties, Showed Antiarrhythmic and Hypotensive Effects in Rats
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DOI: 10.3390/ph15101256
Abstract: Arrhythmia, an irregular heartbeat, might be a life-threatening condition but also a risk factor for stroke or worsen the prognosis after myocardial infarction. The limited efficacy and proarrhythmic potential of the available drugs require searching… read more here.
Keywords: properties showed; compound adrenolytic; adrenolytic properties; antiarrhythmic hypotensive ... See more keywords