The testicular protective effects of standardised hydroalcoholic extract of Ziziphus jujuba Mill against adriamycin‐induced toxicity
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DOI: 10.1111/and.13974
Abstract: In this study, because of the anti‐inflammatory and antioxidant effect of the Ziziphus jujuba (ZJ), we assessed the protective properties of the ZJ extract against testis toxicity caused by Adriamycin in the rat. Twenty rats… read more here.
Keywords: ziziphus jujuba; adriamycin; group; hydroalcoholic extract ... See more keywords
miR-16-5p Regulates Ferroptosis by Targeting SLC7A11 in Adriamycin-Induced Ferroptosis in Cardiomyocytes
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DOI: 10.2147/jir.s393646
Abstract: Introduction Adriamycin (ADR) is commonly used in tumor chemotherapy, but its nonreversible cardiotoxicity severely hampers its clinical application. Ferroptosis is an implicated cause of ADR-induced injury. However, the underlying molecular mechanisms remain poorly understood. This… read more here.
Keywords: adr induced; adriamycin; cardiotoxicity; adr ... See more keywords
Apoptosis and remodeling in adriamycin-induced cardiomyopathy rat model
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DOI: 10.3345/kjp.2017.60.11.365
Abstract: Purpose The mechanism for the pathogenesis of adriamycin (ADR)-induced cardiomyopathy is not yet known. Different hypotheses include the production of free radicals, an interaction between ADR and nuclear components, and a disruption in cardiac-specific gene… read more here.
Keywords: collagen; adriamycin; group; adr induced ... See more keywords
Therapeutic Potential of Astragaloside IV Against Adriamycin-Induced Renal Damage in Rats via Ferroptosis
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DOI: 10.3389/fphar.2022.812594
Abstract: Adriamycin (ADR) has been utilized to treat cancer for several decades. However, ADR-induced renal injury is one of the most common side effects accompanying ADR therapy. In the present study, we revealed that astragaloside IV… read more here.
Keywords: induced renal; adriamycin; asiv; adr ... See more keywords
Heparanase Increases Podocyte Survival and Autophagic Flux after Adriamycin-Induced Injury
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DOI: 10.3390/ijms232012691
Abstract: The kidney glomerular filtration barrier (GFB) is enriched with heparan sulfate (HS) proteoglycans, which contribute to its permselectivity. The endoglycosidase heparanase cleaves HS and hence appears to be involved in the pathogenesis of kidney injury… read more here.
Keywords: heparanase increases; kidney; adriamycin induced; adriamycin ... See more keywords