miR-150 inhibitor ameliorates adriamycin-induced focal segmental glomerulosclerosis.
Sign Up to like & getrecommendations! Published in 2019 at "Biochemical and biophysical research communications"
DOI: 10.1016/j.bbrc.2019.11.096
Abstract: Focal segmental glomerulosclerosis (FSGS) is the most common cause of adult nephrotic syndrome in USA. Its mechanisms remain unclear and the effective treatment lacks. We previously reported that upregulation of microRNA (miR)-150 in human podocytes… read more here.
Keywords: focal segmental; anti mir; mir; adriamycin induced ... See more keywords
Interaction between mTOR pathway inhibition and autophagy induction attenuates adriamycin-induced vascular smooth muscle cell senescence through decreased expressions of p53/p21/p16
Sign Up to like & getrecommendations! Published in 2018 at "Experimental Gerontology"
DOI: 10.1016/j.exger.2017.08.001
Abstract: ABSTRACT Cellular senescence is related to aging and extremely stable proliferative arrest with active metabolism. Senescent cells can activate mammalian target of rapamycin (mTOR) pathway, which plays a crucial role in the regulation of cell… read more here.
Keywords: mtor pathway; inhibition; adriamycin induced; senescence ... See more keywords
Evaluation of injury degree of adriamycin-induced nephropathy in rats based on serum metabolomics combined with proline marker.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of proteome research"
DOI: 10.1021/acs.jproteome.9b00785
Abstract: Nephrotic syndrome (NS) is one of the leading causes of end-stage renal failure. Unfortunately, reliable surrogate markers for early diagnosing and monitoring the entire progression of NS are as yet absent. A method using UPLC-Q… read more here.
Keywords: adriamycin induced; nephropathy rats; proline; induced nephropathy ... See more keywords
Transplantation of mesenchymal stem cells preserves podocyte homeostasis through modulation of parietal epithelial cell activation in adriamycin-induced mouse kidney injury model.
Sign Up to like & getrecommendations! Published in 2020 at "Histology and histopathology"
DOI: 10.14670/hh-18-276
Abstract: To determine the role of the transplantation of bone marrow-derived mesenchymal stem cells (MSCs) in podocyte renewal, we studied BALB/C mice with or without adriamycin-induced acute kidney injury. MSCs were transplanted ectopically under the capsule… read more here.
Keywords: adriamycin induced; kidney injury; mesenchymal stem; stem cells ... See more keywords
Heparanase Increases Podocyte Survival and Autophagic Flux after Adriamycin-Induced Injury
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms232012691
Abstract: The kidney glomerular filtration barrier (GFB) is enriched with heparan sulfate (HS) proteoglycans, which contribute to its permselectivity. The endoglycosidase heparanase cleaves HS and hence appears to be involved in the pathogenesis of kidney injury… read more here.
Keywords: heparanase increases; kidney; adriamycin induced; adriamycin ... See more keywords