Circadian rhythm of the intrarenal renin–angiotensin system is caused by glomerular filtration of liver-derived angiotensinogen depending on glomerular capillary pressure in adriamycin nephropathy rats
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DOI: 10.1038/s41440-021-00620-6
Abstract: Circadian fluctuation disorder of the intrarenal renin–angiotensin system (RAS) causes that of blood pressure (BP) and renal damage. In renal damage with an impaired glomerular filtration barrier, liver-derived angiotensinogen (AGT) filtered through damaged glomeruli regulates… read more here.
Keywords: capillary pressure; adriamycin nephropathy; glomerular capillary; glomerular filtration ... See more keywords
Klotho suppresses the renin-angiotensin system in adriamycin nephropathy
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DOI: 10.1093/ndt/gfw340
Abstract: Backgrounds Klotho protein interacts with the transforming growth factor β (TGF-β) receptor and Wnt, which contribute to the progression of renal disease, inhibiting their signals. Renal and circulating klotho levels are diminished in chronic kidney… read more here.
Keywords: catenin angiotensin; adriamycin nephropathy; angiotensin; expression ... See more keywords