Modification of COL1A1 in Autologous Adipose Tissue‐Derived Progenitor Cells Rescues the Bone Phenotype in a Mouse Model of Osteogenesis Imperfecta
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Bone and Mineral Research"
DOI: 10.1002/jbmr.4326
Abstract: Osteogenesis imperfecta (OI) is a congenital genetic disorder mainly manifested as bone fragility and recurrent fracture. Mutation of COL1A1/COL1A2 genes encoding the type I collagen are most responsible for the clinical patients. Allogenic mesenchymal stem… read more here.
Keywords: adscs; col1a1; bone; osteogenesis imperfecta ... See more keywords
GDNF‐ADSCs‐APG embedding enhances sciatic nerve regeneration after electrical injury in a rat model
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Cellular Biochemistry"
DOI: 10.1002/jcb.28759
Abstract: The pluripotency of adipose‐derived stem cells (ADSCs) makes them appropriate for tissue repair and wound healing. Owing to the repair properties of autologous platelet–rich gel (APG), which is based on easily accessible blood platelets, its… read more here.
Keywords: adscs apg; adscs; gdnf adscs; sciatic nerve ... See more keywords
Exercise ameliorates high‐fat diet‐induced impairment of differentiation of adipose‐derived stem cells into neuron‐like cells in rats
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Cellular Physiology"
DOI: 10.1002/jcp.26957
Abstract: Adipose‐derived stem cells (ADSCs) can differentiate into neurons under particular conditions. It remains largely unknown whether this differentiation potential is affected by physical conditions such as obesity, which modulates the functions of adipose tissue. In… read more here.
Keywords: hfd; adscs; like cells; differentiation ... See more keywords
Enhanced protection against lipopolysaccharide‐induced acute lung injury by autologous transplantation of adipose‐derived stromal cells combined with low tidal volume ventilation in rats
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Cellular Physiology"
DOI: 10.1002/jcp.29936
Abstract: Adipose‐derived stromal cells (ADSCs) showed excellent capacity in regeneration and tissue protection. Low tidal volume ventilation (LVT) strategy demonstrates a therapeutic benefit on the treatment of acute lung injury/acute respiratory distress syndrome (ALI/ARDS). This study,… read more here.
Keywords: protection; derived stromal; adscs; treatment ... See more keywords
The effect of adipose-derived stem cells on enthesis healing after repair of acute and chronic massive rotator cuff tears in rats.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of shoulder and elbow surgery"
DOI: 10.1016/j.jse.2018.08.044
Abstract: BACKGROUND Chronic massive rotator cuff tears heal poorly and often retear. This study investigated the effect of adipose-derived stem cells (ADSCs) and transforming growth factor-β3 (TGF-β3) delivered in 1 of 2 hydrogels (fibrin or gelatin… read more here.
Keywords: rotator cuff; massive rotator; adscs; cuff tears ... See more keywords
TRAF6 promotes osteogenesis in ADSCs through Raf-Erk-Merk-Hif1-a pathway
Sign Up to like & getrecommendations! Published in 2023 at "Adipocyte"
DOI: 10.1080/21623945.2023.2193280
Abstract: ABSTRACT Critical-size defects (CSDs) are challenging oral clinical issues that need to be solved. Adipose-derived mesenchymal stem cells (ADSCs) and gene therapy offer a new target to solve these issues. Consequently, ADSCs attract more and… read more here.
Keywords: raf erk; adscs; traf6; erk merk ... See more keywords
Alteration of transcriptomic profile and anti-septic efficacy of adipose-derived mesenchymal stromal/stem cells under different culture conditions.
Sign Up to like & getrecommendations! Published in 2022 at "Stem cells and development"
DOI: 10.1089/scd.2022.0238
Abstract: Mesenchymal stromal/stem cells (MSCs) are a promising therapeutic agent for various diseases, including sepsis. However, translating MSC therapy to clinical applications remains challenging due to variations in the properties of MSCs under different preparation conditions.… read more here.
Keywords: mesenchymal stromal; adscs; hpl adscs; stromal stem ... See more keywords
Human adipose-derived mesenchymal stem cells-based microspheres ameliorate atherosclerosis progression in vitro.
Sign Up to like & getrecommendations! Published in 2023 at "Stem cells and development"
DOI: 10.1089/scd.2022.0287
Abstract: Atherosclerosis (AS) is a chronic inflammatory disease associated with lipids deposition which could be converted into acute clinical events by thrombosis or plaque rupture. Adipose-derived mesenchymal stem cells (ADSCs) encapsulated repair units could be an… read more here.
Keywords: based microspheres; human adscs; adscs; progression ... See more keywords
E2F1- deficient adipose-derived stem cells improve skin wound closure in mice by upregulating paracrine expression of VEGF and TGF-β1.
Sign Up to like & getrecommendations! Published in 2023 at "Plastic and reconstructive surgery"
DOI: 10.1097/prs.0000000000010145
Abstract: BACKGROUND Wound healing is a widespread health problem that imposes a financial burden on health systems. Cell therapy with genetically modified ADSCs is a promising strategy for dysregulated wound repair. E2F transcription factor 1 is… read more here.
Keywords: e2f1 adscs; adscs; wound closure; vegf tgf ... See more keywords
ADSCs Combined with Melatonin Promote Peripheral Nerve Regeneration through Autophagy
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Endocrinology"
DOI: 10.1155/2022/5861553
Abstract: Background In the early stage of nerve injury, damaged tissue is cleared by autophagy. ADSCs can promote nerve axon regeneration. However, the microenvironment of the injury was changed, and ADSCs are easily apoptotic after transplantation.… read more here.
Keywords: adscs; mel; nerve; group ... See more keywords
Overexpression of PRDX2 in Adipose-Derived Mesenchymal Stem Cells Enhances the Therapeutic Effect in a Neurogenic Erectile Dysfunction Rat Model by Inhibiting Ferroptosis
Sign Up to like & getrecommendations! Published in 2023 at "Oxidative Medicine and Cellular Longevity"
DOI: 10.1155/2023/4952857
Abstract: Neurogenic erectile dysfunction (NED) is a common and serious complication after pelvic surgery. The clinical translation of adipose-derived mesenchymal stem cell (ADSC) therapies in NED remains a major challenge due to their low survival rate… read more here.
Keywords: adscs; erectile dysfunction; therapeutic effect; prdx2 ... See more keywords