Neonatal lipopolysaccharide treatment alters hippocampal neuroinflammation, microglia morphology and anxiety-like behavior in rats selectively bred for an infantile trait
Sign Up to like & getrecommendations! Published in 2017 at "Brain, Behavior, and Immunity"
DOI: 10.1016/j.bbi.2016.08.017
Abstract: Disruptions in homeostasis, such as the induction of inflammation, occurring during the neonatal period of development often produce changes in the brain, physiology, and behavior that persist through the life span. This study investigated the… read more here.
Keywords: anxiety; selectively bred; adult anxiety; like behavior ... See more keywords
Peri-adolescent asthma symptoms cause adult anxiety-related behavior and neurobiological processes in mice
Sign Up to like & getrecommendations! Published in 2017 at "Behavioural Brain Research"
DOI: 10.1016/j.bbr.2017.02.046
Abstract: HighlightsExperimental conditions induced asthma‐like symptoms in adolescent mice.Chronic adolescent asthma symptoms caused adult anxiety‐related symptoms.Induced labored breathing raised adult anxiety behavior and brain gene expression.Induced airway inflammation led to decreased adult basal corticosterone production. Abstract… read more here.
Keywords: anxiety related; anxiety; adult anxiety; labored breathing ... See more keywords
Targeted epigenomic editing ameliorates adult anxiety and excessive drinking after adolescent alcohol exposure
Sign Up to like & getrecommendations! Published in 2022 at "Science Advances"
DOI: 10.1126/sciadv.abn2748
Abstract: Adolescent binge drinking is a major risk factor for psychiatric disorders later in life including alcohol use disorder. Adolescent alcohol exposure induces epigenetic reprogramming at the enhancer region of the activity-regulated cytoskeleton-associated protein (Arc) immediate-early… read more here.
Keywords: alcohol; adolescent alcohol; alcohol exposure; adult anxiety ... See more keywords