DARPP‐32 distinguishes a subset of adult‐born neurons in zebra finch HVC
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Comparative Neurology"
DOI: 10.1002/cne.25245
Abstract: Adult male zebra finches (Taeniopygia guttata) continually incorporate adult‐born neurons into HVC, a telencephalic brain region necessary for the production of learned song. These neurons express activity‐dependent immediate early genes (e.g., zenk and c‐fos) following… read more here.
Keywords: darpp; hvc; hvc nns; adult ... See more keywords
Neuroligin‐2 controls the establishment of fast GABAergic transmission in adult‐born granule cells
Sign Up to like & getrecommendations! Published in 2023 at "Hippocampus"
DOI: 10.1002/hipo.23505
Abstract: GABAergic inhibition is critical for the precision of neuronal spiking and the homeostatic regulation of network activity in the brain. Adult neurogenesis challenges network homeostasis because new granule cells (GCs) integrate continuously in the functional… read more here.
Keywords: fast gabaergic; adult; adult born; granule cells ... See more keywords
Spatial exploration induced expression of immediate early genes Fos and Zif268 in adult-born neurons Is reduced after pentylenetetrazole kindling
Sign Up to like & getrecommendations! Published in 2019 at "Brain Research Bulletin"
DOI: 10.1016/j.brainresbull.2019.07.003
Abstract: Seizure activity stimulates adult neurogenesis, the birth of new neurons, in the hippocampus. Many new neurons that develop in the presence of repeatedly induced seizures acquire abnormal morphological and functional characteristics that can promote network… read more here.
Keywords: adult born; fos zif268; zif268; expression ... See more keywords
Differential Coupling of Adult-Born Granule Cells to Parvalbumin and Somatostatin Interneurons
Sign Up to like & getrecommendations! Published in 2020 at "Cell reports"
DOI: 10.1016/j.celrep.2019.12.005
Abstract: SUMMARY A strong GABAergic tone imposes sparse levels of activity in the dentate gyrus of the hippocampus. This balance is challenged by the addition of new granule cells (GCs) with high excitability. How developing GCs… read more here.
Keywords: adult born; sst ins; granule cells; differential coupling ... See more keywords
Development and Refinement of Functional Properties of Adult-Born Neurons
Sign Up to like & getrecommendations! Published in 2017 at "Neuron"
DOI: 10.1016/j.neuron.2017.09.039
Abstract: New neurons appear only in a few regions of the adult mammalian brain and become integrated into existing circuits. Little is known about the functional development of individual neurons in vivo. We examined the functional life… read more here.
Keywords: development refinement; adult born; refinement functional; born neurons ... See more keywords
Functions of adult-born neurons in hippocampal memory interference and indexing
Sign Up to like & getrecommendations! Published in 2019 at "Nature Neuroscience"
DOI: 10.1038/s41593-019-0484-2
Abstract: The dentate gyrus–CA3 circuit of the hippocampus is continuously modified by the integration of adult-born dentate granule cells (abDGCs). All abDGCs undergo a prolonged period of maturation, during which they exhibit heightened synaptic plasticity and… read more here.
Keywords: adult born; support; memory interference; hippocampal memory ... See more keywords
Recruitment of parvalbumin and somatostatin interneuron inputs to adult born dentate granule neurons
Sign Up to like & getrecommendations! Published in 2020 at "Scientific Reports"
DOI: 10.1038/s41598-020-74385-2
Abstract: GABA is a key regulator of adult-born dentate granule cell (abDGC) maturation so mapping the functional connectivity between abDGCs and local interneurons is required to understand their development and integration into the hippocampal circuit. We… read more here.
Keywords: adult born; dentate granule; born dentate; parvalbumin somatostatin ... See more keywords
Genetic increases in olfactory bulb BDNF do not enhance survival of adult-born granule cells.
Sign Up to like & getrecommendations! Published in 2019 at "Chemical senses"
DOI: 10.1093/chemse/bjz058
Abstract: Adult-born neurons produced in the dentate gyrus subgranular zone (SGZ) develop as excitatory hippocampal granule cells (GCs), while those from the subventricular zone (SVZ) migrate to the olfactory bulb (OB), where most develop as GABAergic… read more here.
Keywords: adult born; olfactory; gcs; survival ... See more keywords
Afferents modulate newborn neurons
Sign Up to like & getrecommendations! Published in 2019 at "Science"
DOI: 10.1126/science.364.6440.542-o
Abstract: Neuroscience What is the role of adult neurogenesis in learning, memory, and mood? Luna et al. found that adult-born neurons either inhibited or excited the dentate gyrus, depending on whether synaptic inputs originated from the… read more here.
Keywords: dentate gyrus; science; adult; afferents modulate ... See more keywords
Adult-born hippocampal neurons bidirectionally modulate entorhinal inputs into the dentate gyrus
Sign Up to like & getrecommendations! Published in 2019 at "Science"
DOI: 10.1126/science.aat8789
Abstract: Afferents modulate newborn neurons What is the role of adult neurogenesis in learning, memory, and mood? Luna et al. found that adult-born neurons either inhibited or excited the dentate gyrus, depending on whether synaptic inputs… read more here.
Keywords: inputs dentate; adult born; dentate gyrus; granule cells ... See more keywords
Multifaceted circuit functions of adult-born neurons
Sign Up to like & getrecommendations! Published in 2019 at "F1000Research"
DOI: 10.12688/f1000research.20642.1
Abstract: The dentate gyrus continually produces new neurons throughout life. Behavioral studies in rodents and network models show that new neurons contribute to normal dentate functions, but there are many unanswered questions about how the relatively… read more here.
Keywords: adult born; multifaceted circuit; born neurons; circuit functions ... See more keywords