SR-mitochondria communication in adult cardiomyocytes: A close relationship where the Ca2+ has a lot to say.
Sign Up to like & getrecommendations! Published in 2019 at "Archives of biochemistry and biophysics"
DOI: 10.1016/j.abb.2019.01.026
Abstract: In adult cardiomyocytes, T-tubules, junctional sarcoplasmic reticulum (jSR), and mitochondria juxtapose each other and form a unique and highly repetitive functional structure along the cell. The close apposition between jSR and mitochondria creates high Ca2+… read more here.
Keywords: adult cardiomyocytes; jsr mitochondria; mitochondrial ca2; ca2 ... See more keywords
Critical appraisal of STAT3 pattern in adult cardiomyocytes.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of molecular and cellular cardiology"
DOI: 10.1016/j.yjmcc.2019.04.021
Abstract: The signal transducer and activator of transcription 3, STAT3, transfers cellular signals from the plasma membrane to the nucleus, acting as a signaling molecule and a transcription factor. Reports proposed an additional non-canonical role of… read more here.
Keywords: adult cardiomyocytes; stat3; mitochondria; ischemia reperfusion ... See more keywords
Loss of Endogenously Cycling Adult Cardiomyocytes Worsens Myocardial Function
Sign Up to like & getrecommendations! Published in 2020 at "Circulation Research"
DOI: 10.1161/circresaha.120.318277
Abstract: Supplemental Digital Content is available in the text. Rationale: Endogenously cycling adult cardiomyocytes increase after myocardial infarction (MI) but remain scarce and are generally thought not to contribute to myocardial function. However, this broadly held… read more here.
Keywords: endogenously cycling; adult cardiomyocytes; cycling adult; adult ... See more keywords
Abstract 214: Effect of Matrix Stiffness on Adult Cardiomyocytes Using Dynamic, Tunable, and Reversible Magnetorheological PDMS Substrates
Sign Up to like & getrecommendations! Published in 2019 at "Circulation Research"
DOI: 10.1161/res.125.suppl_1.214
Abstract: The physical properties of the extracellular matrix (ECM), including stiffness and viscoelasticity, play a key role in the development of hypertensive and hypertrophic cardiac diseases at the cellular level, affecting the morphology and function of… read more here.
Keywords: matrix stiffness; mre; adult cardiomyocytes; stiffness ... See more keywords
Nanoenviroments of the β-Subunit of L-Type Voltage-Gated Calcium Channels in Adult Cardiomyocytes
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Cell and Developmental Biology"
DOI: 10.3389/fcell.2021.724778
Abstract: In cardiomyocytes, Ca2+ influx through L-type voltage-gated calcium channels (LTCCs) following membrane depolarization regulates crucial Ca2+-dependent processes including duration and amplitude of the action potentials and excitation-contraction coupling. LTCCs are heteromultimeric proteins composed of the… read more here.
Keywords: calcium channels; gated calcium; adult cardiomyocytes; voltage gated ... See more keywords
Cell Shortening and Calcium Homeostasis Analysis in Adult Cardiomyocytes via a New Software Tool
Sign Up to like & getrecommendations! Published in 2022 at "Biomedicines"
DOI: 10.3390/biomedicines10030640
Abstract: Intracellular calcium (Ca2+) is the central regulator of heart contractility. Indeed, it couples the electrical signal, which pervades the myocardium, with cardiomyocytes contraction. Moreover, alterations in calcium management are the main factors contributing to the… read more here.
Keywords: tool; analysis; cell shortening; calcium ... See more keywords