Association of high levels of plasma OX40 with acute adult T-cell leukemia
Sign Up to like & getrecommendations! Published in 2019 at "International Journal of Hematology"
DOI: 10.1007/s12185-018-02580-z
Abstract: OX40, a member of the tumor necrosis factor receptor (TNFR) superfamily, co-stimulates activated T cells following interaction with its own ligand OX40L. Human T-cell leukemia virus type-1 (HTLV-1) is an etiological agent of adult T-cell… read more here.
Keywords: acute atl; cell leukemia; adult cell; atl patients ... See more keywords
PD-1 and PD-L1 inhibitors foster the progression of adult T-cell Leukemia/Lymphoma.
Sign Up to like & getrecommendations! Published in 2021 at "International immunopharmacology"
DOI: 10.1016/j.intimp.2021.107870
Abstract: Immunotherapy through immune checkpoints blockade and its subsequent clinical application has revolutionized the treatment of a spectrum of solid tumors. Blockade of Programmed cell death protein-1 and its ligand has shown promising results in clinical… read more here.
Keywords: lymphoma; cell leukemia; leukemia lymphoma; adult cell ... See more keywords
Skin-first nodulotumoral adult T-cell lymphoma mimicking cutaneous T-cell lymphoma
Sign Up to like & getrecommendations! Published in 2019 at "JAAD Case Reports"
DOI: 10.1016/j.jdcr.2019.05.017
Abstract: Adult T-cell leukemia-lymphoma (ATLL) is a peripheral T-cell neoplasm caused by human T-cell lymphotropic virus-1 (HTLV-1) that may resemble other lymphomas clinically and histopathologically. Approximately half of patients with ATLL present with heterogeneous cutaneous findings… read more here.
Keywords: cutaneous cell; adult cell; skin first; cell ... See more keywords
Successful treatment of cutaneous adult T-cell leukemia/lymphoma with imiquimod
Sign Up to like & getrecommendations! Published in 2019 at "JAAD Case Reports"
DOI: 10.1016/j.jdcr.2019.09.019
Abstract: Adult T-cell leukemia/lymphoma (ATL) is a non-Hodgkin lymphoma caused by the human T-lymphotropic virus type 1. The indolent variant manifests on the skin as pruritic papules and plaques. Current treatment regimens for cutaneous ATL include… read more here.
Keywords: cell leukemia; cell; leukemia lymphoma; adult cell ... See more keywords
Adverse prognostic impact of complex karyotype (≥3 cytogenetic alterations) in adult T-cell acute lymphoblastic leukemia (T-ALL).
Sign Up to like & getrecommendations! Published in 2021 at "Leukemia research"
DOI: 10.1016/j.leukres.2021.106612
Abstract: The potential prognostic value of conventional karyotyping in adult T-cell acute lymphoblastic leukemia (T-ALL) remains an open question. We hypothesized that a modified cytogenetic classification, based on the number and type of cytogenetic abnormalities, would… read more here.
Keywords: cytogenetic alterations; cell acute; complex karyotype; lymphoblastic leukemia ... See more keywords
Smoldering adult T-cell leukemia complicated with pneumocystis pneumonia: A case report
Sign Up to like & getrecommendations! Published in 2021 at "Respiratory Medicine Case Reports"
DOI: 10.1016/j.rmcr.2021.101404
Abstract: Adult T-cell leukemia (ATL) is a tumor of CD4-positive T cells that accompanies an infection by human T-cell lymphotropic virus (HTLV-I). ATL is classified into four types—acute, lymphomatous, chronic, and smoldering. Opportunistic infections are known… read more here.
Keywords: pneumocystis pneumonia; adult cell; pneumocystis; case ... See more keywords
Metabolic abnormalities in adult T-cell leukemia/lymphoma and induction of specific leukemic cell death using photodynamic therapy
Sign Up to like & getrecommendations! Published in 2018 at "Scientific Reports"
DOI: 10.1038/s41598-018-33175-7
Abstract: Adult T-cell leukemia/lymphoma (ATL) is an aggressive T-cell neoplasm caused by human T-cell leukemia virus type I (HTLV-I). Therapeutic interventions have not been associated with satisfactory outcomes. We showed that the porphyrin metabolic pathway preferentially… read more here.
Keywords: leukemic cell; cell leukemia; leukemia lymphoma; adult cell ... See more keywords
Pathogenicity and virulence of human T lymphotropic virus type-1 (HTLV-1) in oncogenesis: adult T-cell leukemia/lymphoma (ATLL)
Sign Up to like & getrecommendations! Published in 2023 at "Critical Reviews in Clinical Laboratory Sciences"
DOI: 10.1080/10408363.2022.2157791
Abstract: Abstract Adult T-cell leukemia/lymphoma (ATLL) is an aggressive malignancy of CD4+ T lymphocytes caused by human T lymphotropic virus type-1 (HTLV-1) infection. HTLV-1 was brought to the World Health Organization (WHO) and researchers to address… read more here.
Keywords: cell; leukemia lymphoma; adult cell; cell leukemia ... See more keywords
A genetic IFN/STAT1/FAS axis determines CD4 T stem cell memory levels and apoptosis in healthy controls and Adult T-cell Leukemia patients
Sign Up to like & getrecommendations! Published in 2018 at "Oncoimmunology"
DOI: 10.1080/2162402x.2018.1426423
Abstract: ABSTRACT Adult T-cell leukemia (ATL) is an aggressive, chemotherapy-resistant CD4+CD25+ leukemia caused by HTLV-1 infection, which usually develops in a minority of patients several decades after infection. IFN + AZT combination therapy has shown clinical… read more here.
Keywords: fas; apoptosis; ifn; tscm ... See more keywords
High NAMPT expression and anti-tumour activity of NAMPT inhibitor in adult T-cell leukemia/lymphoma
Sign Up to like & getrecommendations! Published in 2019 at "Annals of Oncology"
DOI: 10.1093/annonc/mdz244.067
Abstract: Abstract Background Adult T-cell leukemia/lymphoma (ATL) is a malignancy of mature T lymphocytes induced by human T-cell leukemia virus-1, and has a poor outcome. New molecular targets for the prevention and treatment of ATL are… read more here.
Keywords: inhibitor; cell leukemia; adult cell; atl ... See more keywords
CADM1 Overexpression and CD7 Downregulation in Strongyloides stercoralis and HTLV-1 Coinfection as Possible Markers for Adult T-cell Leukemia/Lymphoma progression
Sign Up to like & getrecommendations! Published in 2017 at "Open Forum Infectious Diseases"
DOI: 10.1093/ofid/ofx163.170
Abstract: Abstract Background Human T-cell lymphotropic virus (HTLV-1) is a retrovirus endemic in Latin America, Africa, and Asia. Increasing numbers are being reported in the United States. HTLV-1 causes Adult T-cell Leukemia/Lymphoma (ATL) in 3–5% of… read more here.
Keywords: htlv; cell leukemia; infection; adult cell ... See more keywords