Non-additive and epistatic effects of HLA polymorphisms contributing to risk of adult glioma
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Neuro-Oncology"
DOI: 10.1007/s11060-017-2569-7
Abstract: Although genome-wide association studies have identified several susceptibility loci for adult glioma, little is known regarding the potential contribution of genetic variation in the human leukocyte antigen (HLA) region to glioma risk. HLA associations have… read more here.
Keywords: risk; glioma; hla; adult glioma ... See more keywords
PATH-45. CLINICAL UTILITY OF COMBINED NEXT GENERATION SEQUENCING AND CHROMOSOMAL MICROARRAY ANALYSIS FOR THE DIAGNOSIS AND MANAGEMENT OF ADULT GLIOMAS
Sign Up to like & getrecommendations! Published in 2020 at "Neuro-oncology"
DOI: 10.1093/neuonc/noaa215.725
Abstract: Molecular parameters have been incorporated into the 2016 WHO Classification of CNS Tumors and subsequent cIMPACT-NOW updates to facilitate clinical management of glioma patients. However, there have been few reports of the overall clinical utility… read more here.
Keywords: adult; glioma; chromosomal microarray; sequencing chromosomal ... See more keywords
RNA Fusion Transcript Panel Identifies Diverse Repertoire of Fusions in Adult Glioma Patients with Therapeutic Implications
Sign Up to like & getrecommendations! Published in 2023 at "Neuro-Oncology Practice"
DOI: 10.1093/nop/npad022
Abstract: Recurrent gliomas are therapeutically challenging diseases with few treatment options available. One area of potential therapeutic vulnerability is the presence of targetable oncogenic fusion proteins. To better understand the clinical benefit of routinely testing for… read more here.
Keywords: fusion; transcript panel; adult glioma; glioma patients ... See more keywords
Glioma‐induced peritumoral hyperexcitability in a pediatric glioma model
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DOI: 10.14814/phy2.14567
Abstract: Epileptic seizures are among the most common presenting symptom in patients with glioma. The etiology of glioma‐related seizures is complex and not completely understood. Studies using adult glioma patient tissue and adult glioma mouse models,… read more here.
Keywords: pediatric glioma; peritumoral neurons; glioma; adult glioma ... See more keywords
Predictive models and survival analysis of postoperative mental health disturbances in adult glioma patients
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Oncology"
DOI: 10.3389/fonc.2023.1153455
Abstract: Background and Objectives Patients with primary malignant brain tumors may experience mental health disturbances that can significantly affect their daily life. This study aims to identify risk factors and generate predictive models for postoperative mental… read more here.
Keywords: adult glioma; glioma; glioma patients; health disturbances ... See more keywords
Clinical feasibility of modified procarbazine and lomustine chemotherapy without vincristine as a salvage treatment for recurrent adult glioma
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DOI: 10.3892/ol.2022.13234
Abstract: Procarbazine, lomustine and vincristine (PCV) chemotherapy is considered a salvage option for adult glioma; however, its significant toxicities frequently lead to dose reduction or discontinuation in patients with recurrent glioma. The current study evaluated the… read more here.
Keywords: group; adult glioma; chemotherapy; procarbazine lomustine ... See more keywords