Targeting mitochondrial energetics reverses panobinostat- and marizomib-induced resistance in pediatric and adult high-grade gliomas.
Sign Up to like & getrecommendations! Published in 2023 at "Molecular oncology"
DOI: 10.1002/1878-0261.13427
Abstract: In previous studies, we demonstrated that panobinostat, a histone deacetylase inhibitor, and the proteasomal inhibitor bortezomib displayed synergistic therapeutic activity against pediatric and adult high-grade gliomas. Despite the remarkable initial response to this combination, resistance… read more here.
Keywords: adult high; pediatric adult; panobinostat marizomib; gliomas ... See more keywords
Violet Light Transmission is Related to Myopia Progression in Adult High Myopia
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DOI: 10.1038/s41598-017-09388-7
Abstract: Myopia is increasing worldwide. Although the exact etiology of myopia is unknown, outdoor activity is one of the most important environmental factors for myopia control. We previously reported that violet light (VL, 360–400 nm wavelength), which… read more here.
Keywords: high myopia; myopia; myopia progression; adult high ... See more keywords
Pediatric versus adult high grade glioma: Immunotherapeutic and genomic considerations
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2022.1038096
Abstract: High grade gliomas are identified as malignant central nervous tumors that spread rapidly and have a universally poor prognosis. Historically high grade gliomas in the pediatric population have been treated similarly to adult high grade… read more here.
Keywords: adult high; high grade; grade gliomas; grade ... See more keywords