Articles with "adult hippocampal" as a keyword



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Intermittent fasting increases adult hippocampal neurogenesis

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Published in 2019 at "Brain and Behavior"

DOI: 10.1002/brb3.1444

Abstract: Intermittent fasting (IF) has been suggested to have neuroprotective effects through the activation of multiple signaling pathways. Rodents fasted intermittently exhibit enhanced hippocampal neurogenesis and long‐term potentiation (LTP) at hippocampal synapses compared with sedentary animals… read more here.

Keywords: fasting increases; neurogenesis; hippocampal neurogenesis; intermittent fasting ... See more keywords
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Methods to study adult hippocampal neurogenesis in humans and across the phylogeny

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Published in 2022 at "Hippocampus"

DOI: 10.1002/hipo.23474

Abstract: The hippocampus hosts the continuous addition of new neurons throughout life—a phenomenon named adult hippocampal neurogenesis (AHN). Here we revisit the occurrence of AHN in more than 110 mammalian species, including humans, and discuss the… read more here.

Keywords: hippocampal neurogenesis; adult hippocampal; ahn; methodology ... See more keywords
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Mechanisms underlying the effect of voluntary running on adult hippocampal neurogenesis

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Published in 2023 at "Hippocampus"

DOI: 10.1002/hipo.23520

Abstract: Adult hippocampal neurogenesis is important for preserving learning and memory‐related cognitive functions. Physical exercise, especially voluntary running, is one of the strongest stimuli to promote neurogenesis and has beneficial effects on cognitive functions. Voluntary running… read more here.

Keywords: adult hippocampal; mechanisms underlying; neurogenesis; hippocampal neurogenesis ... See more keywords
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ATP6AP2 over-expression causes morphological alterations in the hippocampus and in hippocampus-related behaviour

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Published in 2018 at "Brain Structure and Function"

DOI: 10.1007/s00429-018-1633-1

Abstract: The (pro)renin receptor [(P)RR], also known as ATP6AP2 [ATPase 6 accessory protein 2], is highly expressed in the brain. ATP6AP2 plays a role in early brain development, adult hippocampal neurogenesis and in cognitive functions. Lack… read more here.

Keywords: cell proliferation; atp6ap2 expression; expression; adult hippocampal ... See more keywords
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Targeting impaired adult hippocampal neurogenesis in ageing by leveraging intrinsic mechanisms regulating Neural Stem Cell activity

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Published in 2021 at "Ageing Research Reviews"

DOI: 10.1016/j.arr.2021.101447

Abstract: Deficits in adult neurogenesis may contribute to the aetiology of many neurodevelopmental, psychiatric and neurodegenerative diseases. Genetic ablation of neurogenesis provides proof of concept that adult neurogenesis is required to sustain complex and dynamic cognitive… read more here.

Keywords: adult; neurogenesis; hippocampal neurogenesis; adult hippocampal ... See more keywords
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Distinct function of miR-17-92 cluster in the dorsal and ventral adult hippocampal neurogenesis.

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Published in 2018 at "Biochemical and biophysical research communications"

DOI: 10.1016/j.bbrc.2018.07.086

Abstract: It has been known that the dorsal and ventral areas of the dentate gyrus in the hippocampus have distinct roles in memory and mood behaviors. We previously reported that microRNA miR-17-92 regulates adult hippocampal neurogenesis… read more here.

Keywords: hippocampal neurogenesis; mir; dentate gyrus; dorsal ventral ... See more keywords
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Adult hippocampal neurogenesis as a target for cocaine addiction: a review of recent developments.

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Published in 2019 at "Current opinion in pharmacology"

DOI: 10.1016/j.coph.2019.10.002

Abstract: Basic research in rodents has shown that adult hippocampal neurogenesis (AHN) plays a key role in neuropsychiatric disorders that compromise hippocampal functioning. The discovery that dependence-inducing drugs regulate AHN has led to escalating interest in… read more here.

Keywords: addiction; hippocampal neurogenesis; neurogenesis target; adult hippocampal ... See more keywords
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Withdrawal notice to: Adult hippocampal neurogenesis and antidepressants effects [COPHAR, 50 2020, 17-24].

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Published in 2020 at "Current opinion in pharmacology"

DOI: 10.1016/j.coph.2020.08.001

Abstract: This article has been withdrawn: please see Elsevier Policy on Article Withdrawal (http://www.elsevier.com/locate/withdrawalpolicy). This article has been withdrawn at the request of the editor and publisher. The publisher regrets that an error occurred which led… read more here.

Keywords: article; hippocampal neurogenesis; notice adult; withdrawal notice ... See more keywords
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Impaired adult hippocampal neurogenesis in a mouse model of familial hypercholesterolemia: A role for the LDL receptor and cholesterol metabolism in adult neural precursor cells

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Published in 2019 at "Molecular Metabolism"

DOI: 10.1016/j.molmet.2019.09.002

Abstract: Objective In familial hypercholesterolemia (FH), mutations in the low-density lipoprotein (LDL) receptor (LDLr) gene result in increased plasma LDL cholesterol. Clinical and preclinical studies have revealed an association between FH and hippocampus-related memory and mood… read more here.

Keywords: adult; hippocampal neurogenesis; ldl; cholesterol ... See more keywords
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The regulative effects of levetiracetam on adult hippocampal neurogenesis in mice via Wnt/β-catenin signaling

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Published in 2020 at "Neurochemistry International"

DOI: 10.1016/j.neuint.2019.104643

Abstract: Adult hippocampal neurogenesis plays the pivotal roles in central nervous system diseases. Recently, it has been reported that levetiracetam (LEV), a new antiepileptic drug with novel chemical construction and unique pharmacological properties, suppressed aberrant adult… read more here.

Keywords: adult; hippocampal neurogenesis; catenin; adult hippocampal ... See more keywords
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Waiting impulsivity during reward seeking increases adult hippocampal neurogenesis in mice

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Published in 2019 at "Neuroscience Letters"

DOI: 10.1016/j.neulet.2019.05.032

Abstract: Impulsivity is defined as a predisposition toward rapid, unplanned reactions in response to internal or external stimuli, often yielding negative consequences. Accordingly, impulsivity is considered a significant risk factor for developing addictive behaviors. The hippocampus… read more here.

Keywords: hippocampal neurogenesis; reward seeking; mice; adult hippocampal ... See more keywords