Identification of NeuN immunopositive cells in the adult mouse subventricular zone
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Comparative Neurology"
DOI: 10.1002/cne.24463
Abstract: In the adult rodent subventricular zone (SVZ), there are neural stem cells (NSCs) and the specialized neurogenic niche is critical to maintain their stemness. To date, many cellular and noncellular factors that compose the neurogenic… read more here.
Keywords: subventricular zone; adult mouse; svz; immunopositive cells ... See more keywords
RNA sequencing and expression analysis reveal a role for Lhx9 in the haploinsufficient adult mouse ovary
Sign Up to like & getrecommendations! Published in 2023 at "Molecular Reproduction and Development"
DOI: 10.1002/mrd.23686
Abstract: Understanding the molecular pathways that underpin ovarian development and function is vital for improving the research approaches to investigating fertility. Despite a significant improvement in our knowledge of molecular activity in the ovary, many questions… read more here.
Keywords: adult mouse; mouse ovary; lhx9; expression ... See more keywords
Isolation and Phenotyping of Adult Mouse Microglial Cells.
Sign Up to like & getrecommendations! Published in 2018 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-7837-3_7
Abstract: Microglia are the resident macrophages of the central nervous system parenchyma and fulfill crucial roles in brain development, homeostasis, and inflammation. The isolation of a pure microglia population from brain tissue enables the examination of… read more here.
Keywords: adult mouse; microglial cells; isolation; brain ... See more keywords
Chronic atypical antipsychotics, but not haloperidol, increase neurogenesis in the hippocampus of adult mouse
Sign Up to like & getrecommendations! Published in 2017 at "Brain Research"
DOI: 10.1016/j.brainres.2017.09.006
Abstract: It is suggested that altered neuroplasticity contributes to the pathophysiology of schizophrenia and antipsychotics may exhibit some of their therapeutic efficacies by improving neurogenesis and/or proliferation of neural progenitors. The aim of this study is… read more here.
Keywords: adult mouse; neurogenesis; brdu positive; hippocampus ... See more keywords
Astrocytic mitochondria in adult mouse brain slices show spontaneous calcium influx events with unique properties.
Sign Up to like & getrecommendations! Published in 2021 at "Cell calcium"
DOI: 10.1016/j.ceca.2021.102383
Abstract: Astrocytes govern critical aspects of brain function via spontaneous calcium signals in their soma and processes. A significant proportion of these spontaneous astrocytic calcium events are associated with mitochondria, however, the extent, sources, or kinetics… read more here.
Keywords: adult mouse; spontaneous calcium; astrocytic mitochondria; calcium ... See more keywords
An atlas of gene regulatory elements in adult mouse cerebrum
Sign Up to like & getrecommendations! Published in 2021 at "Nature"
DOI: 10.1038/s41586-021-03604-1
Abstract: The mammalian cerebrum performs high-level sensory perception, motor control and cognitive functions through highly specialized cortical and subcortical structures1. Recent surveys of mouse and human brains with single-cell transcriptomics2–6 and high-throughput imaging technologies7,8 have uncovered… read more here.
Keywords: adult mouse; gene regulatory; cell types; cell ... See more keywords
Identification of Newly Committed Pancreatic Cells in the Adult Mouse Pancreas
Sign Up to like & getrecommendations! Published in 2017 at "Scientific Reports"
DOI: 10.1038/s41598-017-17884-z
Abstract: Multipotent epithelial cells with high Aldehyde dehydrogenase activity have been previously reported to exist in the adult pancreas. However, whether they represent true progenitor cells remains controversial. In this study, we isolated and characterized cells… read more here.
Keywords: adult; adult mouse; mouse pancreas; cells adult ... See more keywords
Optimized Langendorff perfusion system for cardiomyocyte isolation in adult mouse heart
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Cellular and Molecular Medicine"
DOI: 10.1111/jcmm.15773
Abstract: With the rapid development of single‐cell sequencing technology, the Langendorff perfusion system has emerged as a common approach to decompose cardiac tissue and obtain living cardiomyocytes to study cardiovascular disease with the mechanism of cardiomyocyte… read more here.
Keywords: system; langendorff perfusion; perfusion; perfusion system ... See more keywords
The subcommissural organ maintains features of neuroepithelial cells in the adult mouse
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Anatomy"
DOI: 10.1111/joa.13709
Abstract: The subcommissural organ (SCO) is a part of the circumventricular organs located in the dorsocaudal region of the third ventricle at the entrance of the aqueduct of Sylvius. The SCO comprises epithelial cells and produces… read more here.
Keywords: adult; brain; adult mouse; sco cells ... See more keywords
Molecular atlas of the adult mouse brain
Sign Up to like & getrecommendations! Published in 2020 at "Science Advances"
DOI: 10.1126/sciadv.abb3446
Abstract: Whole-brain spatial transcriptomics redefines the neuroanatomical classification of the adult mouse brain. Brain maps are essential for integrating information and interpreting the structure-function relationship of circuits and behavior. We aimed to generate a systematic classification… read more here.
Keywords: adult mouse; brain; mouse brain; molecular atlas ... See more keywords
Reprogramming Müller glia to regenerate ganglion-like cells in adult mouse retina with developmental transcription factors
Sign Up to like & getrecommendations! Published in 2022 at "Science Advances"
DOI: 10.1126/sciadv.abq7219
Abstract: Many neurodegenerative diseases cause degeneration of specific types of neurons. For example, glaucoma leads to death of retinal ganglion cells, leaving other neurons intact. Neurons are not regenerated in the adult mammalian central nervous system.… read more here.
Keywords: ller glia; ganglion; ganglion like; adult mouse ... See more keywords