Trehalose as glucose surrogate in proliferation and cellular mobility of adult neural progenitor cells derived from mouse hippocampus
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Neural Transmission"
DOI: 10.1007/s00702-019-02070-4
Abstract: The disaccharide trehalose (TRE) represents a natural energy supply for distinct non-mammalian species. Evidence has shown that TRE impacts on various properties including the stabilization of protein structure and cell membranes, which are important neuroprotective… read more here.
Keywords: neural progenitor; progenitor cells; adult neural; proliferation ... See more keywords
Gene regulation in adult neural stem cells. Current challenges and possible applications.
Sign Up to like & getrecommendations! Published in 2017 at "Advanced drug delivery reviews"
DOI: 10.1016/j.addr.2017.07.016
Abstract: Adult neural stem and progenitor cells (NSPCs) offer a unique opportunity for neural regeneration and niche modification in physiopathological conditions, harnessing the capability to modify from neuronal circuits to glial scar. Findings exposing the vast… read more here.
Keywords: gene regulation; regulation adult; adult neural; stem cells ... See more keywords
Demyelination Regulates the Circadian Transcription Factor BMAL1 to Signal Adult Neural Stem Cells to Initiate Oligodendrogenesis.
Sign Up to like & getrecommendations! Published in 2020 at "Cell reports"
DOI: 10.1016/j.celrep.2020.108394
Abstract: Circadian clocks are endogenous oscillators that generate cell-autonomous rhythms that govern cellular processes and are synchronized by external cues in the local macro- and micro-environments. Demyelination, a common brain pathology with variable degrees of recovery,… read more here.
Keywords: adult neural; circadian transcription; transcription factor; circadian clocks ... See more keywords
Interleukin-6 Regulates Adult Neural Stem Cell Numbers during Normal and Abnormal Post-natal Development
Sign Up to like & getrecommendations! Published in 2018 at "Stem Cell Reports"
DOI: 10.1016/j.stemcr.2018.03.008
Abstract: Summary Circulating systemic factors can regulate adult neural stem cell (NSC) biology, but the identity of these circulating cues is still being defined. Here, we have focused on the cytokine interleukin-6 (IL-6), since increased circulating… read more here.
Keywords: post natal; stem cell; adult neural;
Manipulating adult neural stem and progenitor cells with G-quadruplex ligands.
Sign Up to like & getrecommendations! Published in 2020 at "ACS chemical neuroscience"
DOI: 10.1021/acschemneuro.0c00194
Abstract: G-quadruplexes are pervasive nucleic acid secondary structures in mammalian genomes and transcriptomes that regulate gene expression and genome duplication. Small molecule ligands that modify the stability of G-quadruplexes are widely studied in cancer, but whether… read more here.
Keywords: adult neural; quadruplex ligands; progenitor cells; neural stem ... See more keywords
Adult Neural Stem Cell Regulation by Small Non-coding RNAs: Physiological Significance and Pathological Implications
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Cellular Neuroscience"
DOI: 10.3389/fncel.2021.781434
Abstract: The adult neurogenic niches are complex multicellular systems, receiving regulatory input from a multitude of intracellular, juxtacrine, and paracrine signals and biological pathways. Within the niches, adult neural stem cells (aNSCs) generate astrocytic and neuronal… read more here.
Keywords: coding rnas; neural stem; adult neural; regulation ... See more keywords
Adult neural stem cells and schizophrenia
Sign Up to like & getrecommendations! Published in 2022 at "World Journal of Stem Cells"
DOI: 10.4252/wjsc.v14.i3.219
Abstract: Schizophrenia (SCZ) is a devastating and complicated mental disorder accompanied by variable positive and negative symptoms and cognitive deficits. Although many genetic risk factors have been identified, SCZ is also considered as a neurodevelopmental disorder.… read more here.
Keywords: neural stem; adult neural; cells schizophrenia; scz ... See more keywords