Articles with "adult rat" as a keyword



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Purification of Clathrin-Coated Vesicles from Adult Rat Brain.

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Published in 2018 at "Methods in molecular biology"

DOI: 10.1007/978-1-4939-8719-1_1

Abstract: Here, we describe a purification protocol for isolating clathrin-coated vesicles (CCVs) from adult rat brain by using differential centrifugation coupled with Ficoll-sucrose and D2O-sucrose density gradient centrifugation and an additional linear sucrose step gradient at… read more here.

Keywords: adult rat; purification; clathrin coated; rat brain ... See more keywords
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Application of the sodium hyaluronate-CNTF scaffolds in repairing adult rat spinal cord injury and facilitating neural network formation

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Published in 2017 at "Science China Life Sciences"

DOI: 10.1007/s11427-017-9217-2

Abstract: The present study aimed to explore the potential of the sodium hyaluronate-CNTF (ciliary neurotrophic factor) scaffold in activating endogenous neurogenesis and facilitating neural network re-formation after the adult rat spinal cord injury (SCI). After completely… read more here.

Keywords: adult rat; hyaluronate cntf; sodium hyaluronate; neural network ... See more keywords
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Transmigration of macrophages through primary adult rat Sertoli cells

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Published in 2022 at "Tissue Barriers"

DOI: 10.1080/21688370.2022.2064179

Abstract: ABSTRACT The blood testis barrier (BTB) is often studied with isolated immature Sertoli cells (SCs), transepithelial resistance (TER) measurements and FITC dextran diffusion assays. Recently, it was found that even in the absence of SCs,… read more here.

Keywords: transmigration; primary adult; rat; adult rat ... See more keywords
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A Clinically Relevant Closed-Head Model of Single and Repeat Concussive Injury in the Adult Rat Using a Controlled Cortical Impact Device.

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Published in 2017 at "Journal of Neurotrauma"

DOI: 10.1089/neu.2016.4517

Abstract: Abstract Repeat concussions (RC) can result in significant long-term neurological consequences and increased risk for neurodegenerative disease compared with single concussion (SC). Mechanisms underlying this difference are poorly understood and best elucidated using an animal… read more here.

Keywords: adult; adult rat; closed head; repeat ... See more keywords
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Positive Modulation of AMPA Receptors Promotes Survival and Proliferation of Neural Stem/Progenitor Cells from the Adult Rat Spinal Cord.

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Published in 2017 at "Stem cells and development"

DOI: 10.1089/scd.2017.0182

Abstract: Transplantation of neural stem/progenitor cells (NSPCs) following spinal cord injury (SCI) is a promising strategy to enhance regeneration but is limited by poor survival of grafted cells. Determining methods to enhance survival of NSPCs is… read more here.

Keywords: ampa; adult rat; rat spinal; stem ... See more keywords
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In utero exposure to low doses of genistein and di‐(2‐ethylhexyl) phthalate (DEHP) alters innate immune cells in neonatal and adult rat testes

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Published in 2020 at "Andrology"

DOI: 10.1111/andr.12840

Abstract: Although humans are exposed to mixtures of endocrine disruptor chemicals, few studies have examined their toxicity on male reproduction. We previously found that fetal exposure to a mixture of the phytoestrogen genistein (GEN) and the… read more here.

Keywords: rat testes; phthalate dehp; adult rat; exposure ... See more keywords
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Orexin enhances neuronal synchronization in adult rat hypothalamic culture: A model to study hypothalamic function.

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Published in 2022 at "Journal of neurophysiology"

DOI: 10.1152/jn.00041.2022

Abstract: The regulation of sleep/wake behavior and energy-homeostasis is maintained in part by the lateral-hypothalamic (LH) neuropeptide orexin-A (OXA, hypocretin). Reduction in OXA-signaling is associated with sleep disorders and obesity, whereas higher OXA-signaling promotes obesity resistance.… read more here.

Keywords: orexin; adult; model study; adult rat ... See more keywords
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Catestatin Induces Glucose Uptake and GLUT4 Trafficking in Adult Rat Cardiomyocytes

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Published in 2018 at "BioMed Research International"

DOI: 10.1155/2018/2086109

Abstract: Catestatin is a cationic and hydrophobic peptide derived from the enzymatic cleavage of the prohormone Chromogranin A. Initially identified as a potent endogenous nicotinic–cholinergic antagonist, Catestatin has recently been shown to act as a novel… read more here.

Keywords: glut4 trafficking; adult rat; catestatin; glucose uptake ... See more keywords
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Melatonin Attenuates Methotrexate-Induced Reduction of Antioxidant Activity Related to Decreases of Neurogenesis in Adult Rat Hippocampus and Prefrontal Cortex

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Published in 2022 at "Oxidative Medicine and Cellular Longevity"

DOI: 10.1155/2022/1596362

Abstract: Previous studies have revealed that the side effects of anticancer drugs induce a decrease of neurogenesis. Methotrexate (MTX), one of anticancer drugs, can induce lipid peroxidation as an indicator of oxidative stress in the brain.… read more here.

Keywords: mtx; adult rat; hippocampus prefrontal; rat hippocampus ... See more keywords
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Oligodendroglia Generated From Adult Rat Adipose Tissue by Direct Cell Conversion

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Published in 2022 at "Frontiers in Cell and Developmental Biology"

DOI: 10.3389/fcell.2022.741499

Abstract: Obtaining oligodendroglial cells from dispensable tissues would be of great interest for autologous or immunocompatible cell replacement therapy in demyelinating diseases, as well as for studying myelin-related pathologies or testing therapeutic approaches in culture. We… read more here.

Keywords: generated adult; conversion; rat; rat adipose ... See more keywords
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Trimethylamine N-Oxide Does Not Impact Viability, ROS Production, and Mitochondrial Membrane Potential of Adult Rat Cardiomyocytes

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Published in 2019 at "International Journal of Molecular Sciences"

DOI: 10.3390/ijms20123045

Abstract: Trimethylamine N-oxide (TMAO) is an organic compound derived from dietary choline and L-carnitine. It behaves as an osmolyte, a protein stabilizer, and an electron acceptor, showing different biological functions in different animals. Recent works point… read more here.

Keywords: adult rat; tmao; trimethylamine oxide; membrane potential ... See more keywords