Casein kinase I inhibitor D4476 influences autophagy and apoptosis in chloroquine-induced adult retinal pigment epithelial-19 cells.
Sign Up to like & getrecommendations! Published in 2022 at "Experimental eye research"
DOI: 10.1016/j.exer.2022.109004
Abstract: The antimalarial drug chloroquine (CQ) induces retinopathy, a disorder characterized by lysosomotropic alteration. In this study, we examined whether D4476 (4-(4-(2,3-dihydrobenzo [1,4] dioxin-6-yl)-5-pyridin-2-yl-1H-imidazol-2-yl) benzamide), a specific casein kinase 1 inhibitor, alleviate CQ-induced retinopathy in adult… read more here.
Keywords: kinase inhibitor; casein kinase; arpe cells; adult retinal ... See more keywords
Adult Goat Retinal Neuronal Culture: Applications in Modeling Hyperglycemia
Sign Up to like & getrecommendations! Published in 2019 at "Frontiers in Neuroscience"
DOI: 10.3389/fnins.2019.00983
Abstract: Culture of adult neurons of the central nervous system (CNS) can provide a unique model system to explore neurodegenerative diseases. The CNS includes neurons and glia of the brain, spinal cord and retina. Neurons in… read more here.
Keywords: adult; adult retinal; retinal neurons; adult goat ... See more keywords