Single Ascending-Dose Study To Evaluate the Safety, Tolerability, and Pharmacokinetics of Sutezolid in Healthy Adult Subjects
Sign Up to like & getrecommendations! Published in 2022 at "Antimicrobial Agents and Chemotherapy"
DOI: 10.1128/aac.02108-21
Abstract: The primary objective of the study was to evaluate the safety and tolerability of single oral doses of sutezolid tablets administered under fasting conditions in healthy adult subjects. The secondary objective was to determine the… read more here.
Keywords: study evaluate; evaluate safety; healthy adult; adult subjects ... See more keywords
Abstract CT192: Phase 1, open-label, single-dose study to evaluate the effect of hepatic impairment on the pharmacokinetics and safety of futibatinib in adult subjects
Sign Up to like & getrecommendations! Published in 2023 at "Cancer Research"
DOI: 10.1158/1538-7445.am2023-ct192
Abstract: Background: Futibatinib, an irreversible FGFR1-4 inhibitor, is indicated for the treatment of adult patients with previously treated, unresectable, locally advanced or metastatic intrahepatic cholangiocarcinoma harboring FGFR2 gene fusions or other rearrangements. As the primary elimination… read more here.
Keywords: futibatinib; study evaluate; adult subjects; evaluate effect ... See more keywords
High Dosage of Botulinum Toxin Type A in Adult Subjects with Spasticity Following Acquired Central Nervous System Damage: Where Are We at?
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DOI: 10.3390/toxins12050315
Abstract: Spasticity is a common disabling disorder in adult subjects suffering from stroke, brain injury, multiple sclerosis (MS) and spinal cord injury (SCI). Spasticity may be a disabling symptom in people during rehabilitation and botulinum toxin… read more here.
Keywords: toxin type; spasticity; dosage; high dosage ... See more keywords
Reliability of Cardiorespiratory and Metabolic Responses During Incremental Shuttle Walk Test in Adult Subjects With Asthma
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DOI: 10.4187/respcare.06112
Abstract: BACKGROUND: The incremental shuttle walk test (ISWT) has been widely used to assess exercise capacity of subjects with COPD. However, to date, no studies have assessed its reliability in the asthmatic population. This study aimed… read more here.
Keywords: metabolic responses; adult subjects; test; reliability ... See more keywords