The synergistic effect between adult weight changes and CYP24A1 polymorphisms is associated with pre- and postmenopausal breast cancer risk
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DOI: 10.1007/s10549-019-05484-6
Abstract: Vitamin D (VD) metabolism regulates adipose tissue, lipogenesis inflammation, and tumor growth. CYP24A1 is the key enzyme for metabolic inactivation of active VD (1,25(OH)2D3). We examined whether common germline single nucleotide polymorphisms (SNPs) in the… read more here.
Keywords: risk; breast cancer; adult weight; postmenopausal ... See more keywords
Long-term excess body fat in adulthood and the risk of pre- and postmenopausal breast cancer in Chinese women
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DOI: 10.1007/s10549-020-05685-4
Abstract: Purpose This study aimed to investigate the association between long-term excess body fat and breast cancer risk by studying adult weight gain together with the subsequent weight fluctuations. Methods Weight gain measure in three different… read more here.
Keywords: risk; breast cancer; adult weight; postmenopausal ... See more keywords