Precision medicine‐based therapies in advanced colorectal cancer: The University of California San Diego Molecular Tumor Board experience
Sign Up to like & getrecommendations! Published in 2022 at "Molecular Oncology"
DOI: 10.1002/1878-0261.13202
Abstract: Treatment for advanced colorectal cancer is often limited by complex molecular profiles, which promote resistance to systemic agents and targeted monotherapies. Recent studies suggest that a personalized, combinatorial approach of matching drugs to tumor alterations… read more here.
Keywords: advanced colorectal; precision medicine; colorectal cancer; tumor ... See more keywords
Combination of D‐dimer and carcinoembryonic antigen levels as a predictive and prognostic biomarker in advanced colorectal cancer patients
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Cellular Biochemistry"
DOI: 10.1002/jcb.28087
Abstract: In view of the controversial findings on the utility of D‐dimer and carcinoembryonic antigen (CEA) as biomarkers in advanced colorectal cancer (CRC), we evaluated the predictive and prognostic value of the D‐dimer and CEA levels… read more here.
Keywords: advanced colorectal; dimer carcinoembryonic; biomarker; cea ... See more keywords
Deep learning‐based assessment of body composition and liver tumour burden for survival modelling in advanced colorectal cancer
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Cachexia, Sarcopenia and Muscle"
DOI: 10.1002/jcsm.13158
Abstract: Personalized therapy planning remains a significant challenge in advanced colorectal cancer care, despite extensive research on prognostic and predictive markers. A strong correlation of sarcopenia or overall body composition and survival has been described. Here,… read more here.
Keywords: advanced colorectal; body composition; survival; colorectal cancer ... See more keywords
Bladder Invasion in Patients with Advanced Colorectal Carcinoma
Sign Up to like & getrecommendations! Published in 2018 at "Indian Journal of Surgical Oncology"
DOI: 10.1007/s13193-018-0788-9
Abstract: Involvement of the bladder by colorectal cancer is sufficiently rare to be encountered by an individual surgeon on an infrequent basis. Extirpative procedures for advanced colorectal cancers can involve partial/total bladder resections. In patients without… read more here.
Keywords: advanced colorectal; bladder; colorectal cancer; bladder invasion ... See more keywords
Expanding Uses of HIPEC for Locally Advanced Colorectal Cancer: A European Perspective.
Sign Up to like & getrecommendations! Published in 2020 at "Clinics in colon and rectal surgery"
DOI: 10.1055/s-0040-1713742
Abstract: Locally advanced colorectal cancer is a challenge for surgeons and medical oncologist; 10 to 20% colorectal cancer debut as locally advanced disease, with tumors extending through the colon wall with perforation and/or invasion of adjacent… read more here.
Keywords: advanced colorectal; expanding uses; colorectal cancer; uses hipec ... See more keywords
Vascular endothelial growth factor inhibitors promote antitumor responses via tumor microenvironment immunosuppression in advanced colorectal cancer.
Sign Up to like & getrecommendations! Published in 2023 at "Scandinavian journal of gastroenterology"
DOI: 10.1080/00365521.2023.2194011
Abstract: PURPOSE This study aims to investigate changes in the tumor immune environment of patients who underwent therapy with a vascular endothelial growth factor (VEGF) inhibitor for advanced colorectal cancer. METHODS Patients (n = 135) with T3 or… read more here.
Keywords: advanced colorectal; cancer; endothelial growth; colorectal cancer ... See more keywords
Application of tumoroids derived from advanced colorectal cancer patients to predict individual response to chemotherapy
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Chemotherapy"
DOI: 10.1080/1120009x.2022.2045827
Abstract: Abstract Therapeutic approaches of advanced colorectal cancer are more complex, here we present a living biobank of patient-derived tumoroids from advanced colorectal cancer patients and show examples of how these tumoroids can be used to… read more here.
Keywords: advanced colorectal; cancer patients; colorectal cancer; chemotherapy ... See more keywords
Prevalence of Advanced Colorectal Neoplasia in Veterans
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Clinical Gastroenterology"
DOI: 10.1097/mcg.0000000000001402
Abstract: Supplemental Digital Content is available in the text. Goal: We sought to quantify the independent effects of age, sex, and race/ethnicity on risk of colorectal cancer (CRC) and advanced neoplasia (AN) in Veterans. Study: We… read more here.
Keywords: prevalence advanced; advanced colorectal; prevalence; risk ... See more keywords
Advanced colorectal cancer: Redefining the outcome paradigm; balancing cure with quality of life
Sign Up to like & getrecommendations! Published in 2021 at "Colorectal Disease"
DOI: 10.1111/codi.15950
Abstract: In recent decades, the management of colorectal cancer has significantly evolved. These advancements have been reflected in the development of specialist units for advanced colorectal cancer including pelvic exenteration and/or cytoreductive surgery/hyperthermic intraperitoneal chemotherapy (CRSHIPEC)… read more here.
Keywords: cancer; advanced colorectal; care; qol ... See more keywords
Diagnostic capability of colon capsule endoscopy for advanced colorectal cancer: A pilot study
Sign Up to like & getrecommendations! Published in 2017 at "Digestive Endoscopy"
DOI: 10.1111/den.12862
Abstract: Colon capsule endoscopy (CCE) is a safe and effective method for detecting lesions in the colon. However, the sensitivity of CCE in detecting advanced colorectal cancer (CRC) has not been sufficiently evaluated. Therefore, the aim… read more here.
Keywords: advanced colorectal; colon capsule; colorectal cancer; colon ... See more keywords
Derivation and validation of a predictive model for advanced colorectal neoplasia in asymptomatic adults
Sign Up to like & getrecommendations! Published in 2020 at "Gut"
DOI: 10.1136/gutjnl-2020-321698
Abstract: Objective Knowing risk for advanced colorectal neoplasia (AN) could help patients and providers choose among screening tests, improving screening efficiency and uptake. We created a risk prediction model for AN to help decide which test… read more here.
Keywords: advanced colorectal; risk; validation; derivation ... See more keywords