Chromosome 3q arm gain linked to immunotherapy response in advanced cutaneous squamous cell carcinoma.
Sign Up to like & getrecommendations! Published in 2019 at "European journal of cancer"
DOI: 10.1016/j.ejca.2019.03.004
Abstract: AIMS The activity that the immune checkpoint inhibitor (ICI) cemiplimab has recently demonstrated has led to a paradigm shift in the management of patients with advanced cutaneous squamous cell carcinoma (cSCC). To identify predictive biomarkers… read more here.
Keywords: ici; response; cell carcinoma; squamous cell ... See more keywords
Bullous pemphigoid associated with cemiplimab therapy in a patient with locally advanced cutaneous squamous cell carcinoma
Sign Up to like & getrecommendations! Published in 2020 at "JAAD Case Reports"
DOI: 10.1016/j.jdcr.2020.01.008
Abstract: Cemiplimab (Libtayo, Regeneron Pharmaceuticals, Tarrytown, NY) is a monoclonal antibody that targets the programmed cell death receptor 1. In 2018, the Food and Drug Administration approved cemiplimab for the treatment of patients with metastatic cutaneous… read more here.
Keywords: cell carcinoma; squamous cell; cutaneous squamous; locally advanced ... See more keywords
Pembrolizumab as monotherapy in locally advanced cutaneous squamous cell carcinoma
Sign Up to like & getrecommendations! Published in 2022 at "Expert Review of Anticancer Therapy"
DOI: 10.1080/14737140.2022.2125382
Abstract: ABSTRACT Introduction Outcomes for patients with advanced cutaneous squamous cell carcinoma (cSCC) are poor, however recent approvals in programmed death-1 (PD-1) checkpoint inhibition have shown promise. Prior systemic treatments in this patient population included chemotherapy… read more here.
Keywords: locally advanced; cell carcinoma; cutaneous squamous; advanced cutaneous ... See more keywords
Management of elderly patients with advanced cutaneous squamous cell carcinoma.
Sign Up to like & getrecommendations! Published in 2022 at "Japanese journal of clinical oncology"
DOI: 10.1093/jjco/hyab213
Abstract: The incidence of cutaneous squamous cell carcinoma has been increasing rapidly in recent years, especially among the elderly. The purpose of this review article is to summarize the findings of studies on systemic therapy for… read more here.
Keywords: cell carcinoma; squamous cell; cutaneous squamous; advanced cutaneous ... See more keywords
Infrequent liver injury from cemiplimab in patients with advanced cutaneous squamous cell carcinoma.
Sign Up to like & getrecommendations! Published in 2022 at "Immunotherapy"
DOI: 10.2217/imt-2021-0191
Abstract: Aim: To describe the incidence and outcomes of liver injury in patients with advanced cutaneous squamous cell carcinoma (cSCC) receiving cemiplimab. Methods: Charts of cSCC patients receiving cemiplimab between 28 September 2018 and 14 July 2020 were reviewed.… read more here.
Keywords: cutaneous squamous; advanced cutaneous; liver injury; patients advanced ... See more keywords
Serum Level of Soluble CD163 May Be a Predictive Marker of the Effectiveness of Nivolumab in Patients With Advanced Cutaneous Melanoma
Sign Up to like & getrecommendations! Published in 2018 at "Frontiers in Oncology"
DOI: 10.3389/fonc.2018.00530
Abstract: Antibodies against programmed cell death protein 1, such as nivolumab and pembrolizumab, are widely used for treating various cancers, including advanced melanoma. Nivolumab significantly prolongs survival in patients with metastatic melanoma, and sequential administration with… read more here.
Keywords: melanoma; cutaneous melanoma; serum level; patients advanced ... See more keywords
Emerging Novel Therapeutic Approaches for Treatment of Advanced Cutaneous Melanoma
Sign Up to like & getrecommendations! Published in 2022 at "Cancers"
DOI: 10.3390/cancers14020271
Abstract: Simple Summary The introduction of immune checkpoint inhibitors and targeted therapy for the treatment of unresectable advanced or metastatic melanoma has changed the prognosis of melanoma patients. Five-year overall survival rates for metastatic melanoma have… read more here.
Keywords: advanced cutaneous; melanoma; immune checkpoint; therapy ... See more keywords
Real-Life Study of the Benefit of Concomitant Radiotherapy with Cemiplimab in Advanced Cutaneous Squamous Cell Carcinoma (cSCC): A Retrospective Cohort Study
Sign Up to like & getrecommendations! Published in 2023 at "Cancers"
DOI: 10.3390/cancers15020495
Abstract: Simple Summary Cemiplimab is used in the treatment of advanced cutaneous squamous cell carcinoma. Synergistic antitumoral response by concurrent radiotherapy and immunotherapy seems promising. We collected data from patients who were administered cemiplimab in Caen… read more here.
Keywords: advanced cutaneous; radiotherapy; group; cemiplimab ... See more keywords