Will vitamin E be the hope of patients with NASH and advanced fibrosis? - the reliability is worth discussing.
Sign Up to like & getrecommendations! Published in 2019 at "Hepatology"
DOI: 10.1002/hep.30603
Abstract: According to the article conducted by Eduardo et al.(1), the non-transplant survival rate of nonalcoholic steatohepatitis (NASH) patients with bridging necrosis and cirrhosis, which is a subtype of non-alcoholic fatty liver disease (NAFLD), was found to… read more here.
Keywords: patients nash; nash advanced; hope patients; vitamin hope ... See more keywords
Evaluating Noninvasive Markers to Identify Advanced Fibrosis by Liver Biopsy in HBV/HIV Co‐infected Adults
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DOI: 10.1002/hep.30825
Abstract: Noninvasive biomarkers are used increasingly to assess fibrosis in patients with chronic liver disease. We determined the utility of dual cutoffs for noninvasive biomarkers to exclude and confirm advanced fibrosis in hepatitis B virus (HBV)–human… read more here.
Keywords: vcte; fibrosis; hbv; advanced fibrosis ... See more keywords
Noninvasive Tests Accurately Identify Advanced Fibrosis due to NASH: Baseline Data From the STELLAR Trials
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DOI: 10.1002/hep.30842
Abstract: Accurate noninvasive tests (NITs) are needed to replace liver biopsy for identifying advanced fibrosis caused by nonalcoholic steatohepatitis (NASH). We analyzed screening data from two phase 3 trials of selonsertib to assess the ability of… read more here.
Keywords: fibrosis; discriminate advanced; tests accurately; accurately identify ... See more keywords
Letter to the Editor: Chronic Hepatitis B and Nonalcoholic Steatohepatitis: Is “Fat” All Bad?
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DOI: 10.1002/hep.30983
Abstract: We read with interest the recent paper by Choi et al.(1) on the impact of biopsy-proven nonalcoholic steatohepatitis (NASH) on chronic hepatitis B (CHB) outcomes. The study concluded that compared to patients with CHB alone,… read more here.
Keywords: chronic hepatitis; chb; advanced fibrosis; nonalcoholic steatohepatitis ... See more keywords
Stratification of Residual Risk of HCC Following HCV Clearance With Direct‐Acting Antivirals in Patients With Advanced Fibrosis and Cirrhosis
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DOI: 10.1002/hep.31639
Abstract: Hepatitis C virus (HCV) is a major risk factor for hepatocellular carcinoma (HCC), one of the deadliest cancers with increasing incidence over the past few decades (1). Direct-acting antiviral (DAA) therapy in HCV-infected patients has… read more here.
Keywords: risk; hcc; cirrhosis; direct acting ... See more keywords
Combination of PNPLA3 and TLL1 polymorphism can predict advanced fibrosis in Japanese patients with nonalcoholic fatty liver disease
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DOI: 10.1007/s00535-017-1372-8
Abstract: BackgroundHepatic fibrosis is an independent risk factor for mortality and liver-related events in patients with nonalcoholic fatty liver disease (NAFLD). PNPLA3 rs738409 has been associated with fibrosis in viral and non-viral hepatitis. TLL1 rs17047200 also… read more here.
Keywords: risk; tll1; fibrosis; japanese patients ... See more keywords
The Costs of Hepatitis C by Liver Disease Stage: Estimates from the Veterans Health Administration
Sign Up to like & getrecommendations! Published in 2019 at "Applied Health Economics and Health Policy"
DOI: 10.1007/s40258-019-00468-5
Abstract: BackgroundThe release of highly effective but costly medications for the treatment of hepatitis C virus combined with a doubling in the incidence of hepatitis C virus have posed substantial financial challenges for many healthcare systems.… read more here.
Keywords: liver; liver transplant; hepatitis virus; health ... See more keywords
LUM is the hub gene of advanced fibrosis in nonalcoholic fatty liver disease patients.
Sign Up to like & getrecommendations! Published in 2020 at "Clinics and research in hepatology and gastroenterology"
DOI: 10.1016/j.clinre.2020.04.006
Abstract: INTRODUCTION Advanced fibrosis in nonalcoholic fatty liver disease (NAFLD) is associated with a poor prognosis. The genetic factors contributing to fibrosis in NAFLD have been described. However, the genetic mechanism and hub genes of advanced… read more here.
Keywords: hub gene; fibrosis nonalcoholic; nonalcoholic fatty; gene ... See more keywords
Non-invasive assessment of non-alcoholic fatty liver disease: Clinical prediction rules and blood-based biomarkers.
Sign Up to like & getrecommendations! Published in 2018 at "Journal of hepatology"
DOI: 10.1016/j.jhep.2017.11.013
Abstract: The correct identification of patients at increased risk of non-alcoholic steatohepatitis (NASH) and advanced fibrosis is a critical step in the assessment of non-alcoholic fatty liver disease (NAFLD). Since liver biopsy is invasive, expensive and… read more here.
Keywords: fibrosis; non alcoholic; rules blood; clinical prediction ... See more keywords
New sequential combinations of non-invasive fibrosis tests provide an accurate diagnosis of advanced fibrosis in NAFLD.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of hepatology"
DOI: 10.1016/j.jhep.2019.04.020
Abstract: BACKGROUND & AIMS Advanced liver fibrosis is an important diagnostic target in non-alcoholic fatty liver disease (NAFLD) as it defines the subgroup of patients with impaired prognosis. The non-invasive diagnosis of advanced fibrosis is currently… read more here.
Keywords: vcte; fibrosis; diagnosis; diagnosis advanced ... See more keywords
Moderate alcohol consumption is associated with advanced fibrosis in non-alcoholic fatty liver disease and shows a synergistic effect with type 2 diabetes mellitus.
Sign Up to like & getrecommendations! Published in 2020 at "Metabolism: clinical and experimental"
DOI: 10.1016/j.metabol.2020.154439
Abstract: BACKGROUND Non-alcoholic fatty liver disease (NAFLD) is the most common chronic liver disease worldwide. Whether moderate alcohol consumption plays a role for progression of NAFLD is disputed. Moreover, it is not known which tool is… read more here.
Keywords: alcohol consumption; moderate alcohol; advanced fibrosis;