Combined Surgery and Extensive Intraoperative Peritoneal Lavage vs Surgery Alone for Treatment of Locally Advanced Gastric Cancer: The SEIPLUS Randomized Clinical Trial.
Sign Up to like & getrecommendations! Published in 2019 at "JAMA surgery"
DOI: 10.1001/jamasurg.2019.0153
Abstract: Importance Peritoneal metastasis is the most frequent pattern of postoperative recurrence in patients with gastric cancer. Extensive intraoperative peritoneal lavage (EIPL) is a new prophylactic strategy for treatment of peritoneal metastasis of locally advanced gastric… read more here.
Keywords: surgery; advanced gastric; gastric cancer; surgery plus ... See more keywords
Progression patterns and site‐specific responses in advanced gastric cancer patients treated with nivolumab
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DOI: 10.1002/cam4.5689
Abstract: While the efficacy of immune checkpoint inhibitors (ICIs) reportedly varies among metastatic sites and progression patterns (classified as systemic progression [SP] or mixed progression [MP]), the clinical efficacy of ICIs against gastric cancer remains unclear.… read more here.
Keywords: advanced gastric; progression; gastric cancer; site ... See more keywords
Safety and efficacy of trastuzumab administered as a 30-min infusion in patients with HER2-positive advanced gastric cancer
Sign Up to like & getrecommendations! Published in 2018 at "Cancer Chemotherapy and Pharmacology"
DOI: 10.1007/s00280-018-3753-y
Abstract: PurposeTo investigate the safety and efficacy of 30-min maintenance infusions of trastuzumab in advanced gastric cancer positive for human epidermal growth factor receptor 2 (HER2).MethodsThis was a retrospective study conducted across five Korean hospitals in… read more here.
Keywords: advanced gastric; patients her2; infusion; gastric cancer ... See more keywords
Laparoscopic gastrectomy for stage II and III advanced gastric cancer: long‑term follow‑up data from a Western multicenter retrospective study
Sign Up to like & getrecommendations! Published in 2021 at "Surgical Endoscopy"
DOI: 10.1007/s00464-021-08505-y
Abstract: There has been an increasing interest for the laparoscopic treatment of early gastric cancer, especially among Eastern surgeons. However, the oncological effectiveness of Laparoscopic Gastrectomy (LG) for Advanced Gastric Cancer (AGC) remains a subject of… read more here.
Keywords: laparoscopic gastrectomy; advanced gastric; stage iii; gastric cancer ... See more keywords
Comparison of laparoscopic surgery with open standard surgery for advanced gastric carcinoma in a single institute: a propensity score matching analysis
Sign Up to like & getrecommendations! Published in 2021 at "Surgical Endoscopy"
DOI: 10.1007/s00464-021-08652-2
Abstract: Compared with open standard gastrectomy (OG), laparoscopic gastrectomy (LG) did not result in inferior disease-free survival for early-stage and locally advanced gastric cancer (AGC). However, whether LG for AGC in elderly patients is more beneficial… read more here.
Keywords: surgery; advanced gastric; analysis; year ... See more keywords
Impact of diabetes mellitus on long-term prognosis after gastrectomy for advanced gastric cancer: a propensity score matching analysis
Sign Up to like & getrecommendations! Published in 2022 at "Surgery Today"
DOI: 10.1007/s00595-022-02482-y
Abstract: We investigated the long-term prognostic impact of diabetes mellitus (DM) after gastrectomy for advanced gastric cancer. This was a retrospective cohort study of consecutive patients who underwent gastrectomy for primary p-T2 or more advanced-stage gastric… read more here.
Keywords: cancer; analysis; impact diabetes; long term ... See more keywords
Minimally invasive surgery for advanced gastric cancer: are we sure?
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DOI: 10.1007/s10120-017-0727-4
Abstract: We read with particular interest the paper written by Erin K. Greenleaf et al. and published in March 2017 in Gastric Cancer [1]. Their paper reports a comparison of the minimally invasive surgical approach to… read more here.
Keywords: advanced gastric; gastric cancer; minimally invasive; disease ... See more keywords
Association between UGT1A1 gene polymorphism and safety and efficacy of irinotecan monotherapy as the third-line treatment for advanced gastric cancer
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DOI: 10.1007/s10120-018-00917-5
Abstract: BackgroundWhile uridine diphosphate glucuronosyltransferase (UGT) 1A1 is a key enzyme in the metabolism of irinotecan, relationship between UGT1A1 genotype and safety and efficacy of irinotecan monotherapy in patients with advanced gastric cancer is not clarified.MethodsEfficacy… read more here.
Keywords: irinotecan monotherapy; advanced gastric; gastric cancer; treatment ... See more keywords
A multicenter phase II study of TAS-114 in combination with S-1 in patients with pretreated advanced gastric cancer (EPOC1604)
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DOI: 10.1007/s10120-020-01107-y
Abstract: Background This is a phase 2 study aimed at evaluating the efficacy and safety of TAS-114, a novel deoxyuridine triphosphatase inhibitor, combined with S-1 in patients with advanced gastric cancer (AGC). Methods Eligible patients had… read more here.
Keywords: advanced gastric; gastric cancer; months months; phase study ... See more keywords
Human epidermal growth factor receptor 2 (HER2) in advanced gastric cancer: where do we stand?
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DOI: 10.1007/s10120-021-01182-9
Abstract: Gastric cancer is one of the most common malignancy worldwide. In unresectable or metastatic disease, the prognosis is poor and in generally less than a year. HER2 expression remains an important biomarker to lead the… read more here.
Keywords: advanced gastric; gastric cancer; human epidermal; epidermal growth ... See more keywords
Phase II study of S-1 plus oxaliplatin 130 mg/m2 in Japanese patients with advanced gastric cancer
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DOI: 10.1007/s10147-018-1308-1
Abstract: PurposeAlthough oxaliplatin 130 mg/m2 every 3 weeks was approved for advanced gastric cancer in Japan, data regarding S-1 plus oxaliplatin 130 mg/m2 (SOX130) are limited in Japanese patients with advanced gastric cancer. We investigated the feasibility and… read more here.
Keywords: advanced gastric; gastric cancer; japanese patients; patients advanced ... See more keywords