A drop in the circulating concentrations of soluble receptor for advanced glycation end products is associated with seroconversion to autoantibody positivity but not with subsequent progression to clinical disease in children en route to type 1 diabetes
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DOI: 10.1002/dmrr.2872
Abstract: Advanced glycation end products (AGEs) and their interaction with the receptor for AGEs (RAGE) have been studied for their role in the pathogenesis and complications of type 1 diabetes. Decreased concentrations of soluble RAGE (sRAGE)… read more here.
Keywords: concentrations soluble; type diabetes; end products; glycation end ... See more keywords
Dietary Advanced Glycation End Products Have Sex‐ and Age‐Dependent Effects on Vertebral Bone Microstructure and Mechanical Function in Mice
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DOI: 10.1002/jbmr.3321
Abstract: Back pain is a leading cause of global disability that can arise from vertebral fracture and osteoporosis. Although poor general health and obesity are among the strongest risk factors for back pain, there is remarkably… read more here.
Keywords: advanced glycation; age; bone; glycation end ... See more keywords
Dimorphic Mechanisms of Fragility in Diabetes Mellitus: the Role of Reduced Collagen Fibril Deformation
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DOI: 10.1002/jbmr.4706
Abstract: Diabetes mellitus (DM) is an emerging metabolic disease, and the management of diabetic bone disease poses a serious challenge worldwide. Understanding the underlying mechanisms leading to high fracture risk in DM is hence of particular… read more here.
Keywords: deformation; advanced glycation; bone; collagen fibril ... See more keywords
Intrauterine hyperglycemia-induced inflammatory signalling via the receptor for advanced glycation end products in the cardiac muscle of the infants of diabetic mother rats
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DOI: 10.1007/s00394-017-1536-6
Abstract: PurposeGestational diabetes is associated with increased risk to the health of the mother and her offspring. In particular, the infants of diabetic mothers (IDMs) exhibit elevated levels of preterm birth, macrosomia, hypoglycemia, hypocalcemia, and cardiomyopathy.… read more here.
Keywords: intrauterine hyperglycemia; infants diabetic; mother; end products ... See more keywords
Methylglyoxal-derived advanced glycation end products contribute to negative cardiac remodeling and dysfunction post-myocardial infarction
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DOI: 10.1007/s00395-017-0646-x
Abstract: Advanced glycation end-products (AGEs) have been associated with poorer outcomes after myocardial infarction (MI), and linked with heart failure. Methylglyoxal (MG) is considered the most important AGE precursor, but its role in MI is unknown.… read more here.
Keywords: glo1; end products; glycation end; post ... See more keywords
Effect of plant polyphenols on the formation of advanced glycation end products from β-lactoglobulin
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DOI: 10.1007/s10068-017-0053-y
Abstract: Dietary exposure to advanced glycation end products (AGEs) formed from proteins and reducing sugars is of increasing concern to human health. AGEs may form in protein-based powders containing sugars for instant beverages during drying and… read more here.
Keywords: plant; formation; effect; end products ... See more keywords
Advanced glycation end products as a source of artifacts in immunoenzymatic methods
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DOI: 10.1007/s10719-017-9805-4
Abstract: The most abundant proteins in the arteries are those of extracellular matrix, ie. collagen and elastin. Due to their long half-lifes these proteins have an increased chance to undergo glycation. The aim of this study… read more here.
Keywords: advanced glycation; age; end products; glycation end ... See more keywords
Metabolic transit of dietary advanced glycation end-products - the case of NƐ-carboxymethyllysine.
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DOI: 10.1007/s10719-020-09950-y
Abstract: The Maillard reaction, also called glycation, is one of the major chemical reactions responsible for most yellow-to-brown colors and aromas in cooked foods. This reaction between reducing sugars and amino functions on proteins affects not… read more here.
Keywords: advanced glycation; end products; glycation end; metabolic transit ... See more keywords
Evaluation of vitreous levels of advanced glycation end products and angiogenic factors as biomarkers for severity of diabetic retinopathy
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DOI: 10.1007/s10792-017-0499-1
Abstract: Background/AimsGlyceraldehyde-derived advanced glycation end products (glycer-AGE; also called Toxic-AGE [TAGE]) play a crucial role in the pathogenesis of diabetic angiopathy. However, the relationships between vitreous glycer-AGE levels and diabetic retinopathy (DR) severity, and between glycer-AGE… read more here.
Keywords: glycer age; age; glycation end; vitreous levels ... See more keywords
The Impact of Different Drying Techniques and Controlled Storage on the Development of Advanced Glycation End Products in Skim Milk Powders Using Isotope Dilution ESI-LC-MS/MS
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DOI: 10.1007/s11947-017-1936-x
Abstract: The impact of different drying techniques and storage conditions on the formation of carboxymethyl lysine (CML) as an advanced glycation end product (AGE) was investigated in various pilot-scale produced skim milk powders (SMP). CML, an… read more here.
Keywords: storage; drying techniques; impact different; glycation end ... See more keywords
Inhibiting Effect of Zinc Oxide Nanoparticles on Advanced Glycation Products and Oxidative Modifications: a Potential Tool to Counteract Oxidative Stress in Neurodegenerative Diseases
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DOI: 10.1007/s12035-018-0935-x
Abstract: Advanced glycation end products (AGEs) are implicated in several central nervous system (CNS) pathologies including Alzheimer and Parkinson’s diseases. In the face-off of AGE menace, we have attempted to investigate the zinc oxide nanoparticle (ZnONP)… read more here.
Keywords: advanced glycation; age; age formation; zinc oxide ... See more keywords