Quality of life in patients with locally advanced head and neck squamous cell carcinoma undergoing concurrent chemoradiation with once‐a‐week versus once‐every‐3‐weeks cisplatin
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DOI: 10.1002/cam4.4715
Abstract: This trial was conducted to compare the efficacy of low dose once‐a‐week cisplatin and once‐every‐3‐weeks cisplatin with radiation in locally advanced head and neck squamous cell carcinoma (LAHNSCC). The current analysis focuses on the quality… read more here.
Keywords: locally advanced; head neck; advanced head; weeks cisplatin ... See more keywords
A systematic review of neoadjuvant and definitive immunotherapy in locally advanced head and neck squamous cell carcinoma.
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DOI: 10.1002/cam4.5815
Abstract: Patients with locally advanced head and neck squamous cell carcinoma (HNSCC) require multi‐modality treatment. Immune checkpoint inhibitors (ICIs) are now standard of care in management of recurrent/metastatic HNSCC. However, its role in the definitive and… read more here.
Keywords: locally advanced; cell carcinoma; head neck; advanced head ... See more keywords
Phase 1 dose‐finding study of metformin in combination with concurrent cisplatin and radiotherapy in patients with locally advanced head and neck squamous cell cancer
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DOI: 10.1002/cncr.32539
Abstract: The 5‐year overall survival (OS) rate remains at 50% for patients with locally advanced head and neck squamous cell carcinoma (LAHNSCC), thereby underscoring the need for improved treatments. An antidiabetic agent, metformin, was found in… read more here.
Keywords: neck squamous; squamous cell; advanced head; patients locally ... See more keywords
Randomized controlled study comparing simultaneous modulated accelerated radiotherapy versus simultaneous integrated boost intensity modulated radiotherapy in the treatment of locally advanced head and neck cancer.
Sign Up to like & getrecommendations! Published in 2018 at "Journal of the Egyptian National Cancer Institute"
DOI: 10.1016/j.jnci.2018.06.001
Abstract: OBJECTIVES Comparison of two fractionation schedules of intensity modulated radiotherapy (IMRT) for locally advanced head and neck cancer - simultaneous integrated boost (SIB-IMRT) and simultaneous modulated accelerated radiotherapy (SMART) boost in terms of toxicity and… read more here.
Keywords: boost; study; cancer; arm ... See more keywords
nab-Paclitaxel-based induction chemotherapy with or without cetuximab for locally advanced head and neck squamous cell carcinoma.
Sign Up to like & getrecommendations! Published in 2017 at "Oral oncology"
DOI: 10.1016/j.oraloncology.2017.07.001
Abstract: OBJECTIVES To explore the effect of incorporating cetuximab into induction chemotherapy in locally advanced head and neck squamous cell carcinoma (HNSCC). MATERIALS AND METHODS Retrospective comparative analysis of two consecutive prospective phase II trials was… read more here.
Keywords: neck squamous; squamous cell; advanced head; induction chemotherapy ... See more keywords
2D and 3D convolutional neural networks for outcome modelling of locally advanced head and neck squamous cell carcinoma
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DOI: 10.1038/s41598-020-70542-9
Abstract: For treatment individualisation of patients with locally advanced head and neck squamous cell carcinoma (HNSCC) treated with primary radiochemotherapy, we explored the capabilities of different deep learning approaches for predicting loco-regional tumour control (LRC) from… read more here.
Keywords: neck squamous; squamous cell; advanced head; model ... See more keywords
Abstract CT153: Correlation ofCDKN2Agenomic alterations with tumor response to palbociclib given before chemoradiation therapy to patients with human papillomavirus-unrelated, locally advanced head and neck squamous-cell carcinoma
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DOI: 10.1158/1538-7445.am2021-ct153
Abstract: The primary aims of this single-arm, phase 2 trial were to determine the objective response rate (ORR) of human papillomavirus (HPV)-unrelated, locally advanced head and neck squamous-cell carcinoma (LA-HNSCC) to palbociclib monotherapy, and to correlate… read more here.
Keywords: advanced head; locally advanced; unrelated locally; neck squamous ... See more keywords
Comparative efficacy and safety of radiotherapy/cetuximab versus radiotherapy/chemotherapy for locally advanced head and neck squamous cell carcinoma patients: a systematic review of published, primarily non-randomized, data
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DOI: 10.1177/1758835920975355
Abstract: Background: Cetuximab (CTX) has been approved to be administered concurrently with radiotherapy (RT) to treat locally advanced head and neck squamous cell carcinoma (HNSCC). The aim of this study was to assess the efficacy and… read more here.
Keywords: efficacy safety; locally advanced; radiotherapy; advanced head ... See more keywords
Impact of systemic treatment associated to radiotherapy on quality of life in locally advanced head and neck cancer patients in Brazil: Prospective real-world data study.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Clinical Oncology"
DOI: 10.1200/jco.2019.37.15_suppl.e17563
Abstract: e17563 Background: the purpose of this study was to compare quality of life (QoL) and overall survival (OS) in patients with locally advanced head and neck cancer treated with radiotherapy only (RT), chemoradiotherapy with cisplatin… read more here.
Keywords: quality life; qol; advanced head; locally advanced ... See more keywords
Concurrent chemoradiotherapy using gemcitabine and nedaplatin in recurrent or locally advanced head and neck squamous cell carcinoma
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DOI: 10.12998/wjcc.v10.i11.3414
Abstract: BACKGROUND Patients with recurrent or locally advanced head and neck squamous cell carcinoma (HNSCC) typically have limited treatment options and poor prognosis. AIM To evaluate the efficacy and safety of two drugs with potent radio-sensitization… read more here.
Keywords: locally advanced; chemoradiotherapy; head neck; advanced head ... See more keywords
Hearing Loss After Cisplatin-based Chemoradiotherapy for Locally Advanced Head and Neck Cancer: A Prospective Single-institution Study
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DOI: 10.21873/anticanres.15784
Abstract: Background/Aim: A single-institution prospective study was conducted to evaluate hearing loss rate after intensity modulated radiotherapy with concomitant cisplatin-based chemotherapy (CRT) for locally advanced head and neck cancer and identify cochlear dosimetric parameters associated with… read more here.
Keywords: locally advanced; head neck; advanced head; hearing loss ... See more keywords