Gemcitabine and cisplatin regimen facilitates prognosis of advanced nasopharyngeal carcinoma
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DOI: 10.1002/cam4.1575
Abstract: This study was conducted to assess the efficacy and adverse effects of GP (gemcitabine + cisplatin) regimen and FP (fluouracil + cisplatin) regimen in treatment of advanced nasopharyngeal carcinoma. Systematic online searches were performed in… read more here.
Keywords: regimen facilitates; gemcitabine cisplatin; cisplatin regimen; advanced nasopharyngeal ... See more keywords
Raltitrexed versus 5‐fluorouracil with cisplatin and concurrent radiotherapy for locally advanced nasopharyngeal carcinoma: An open labeled, randomized, controlled, and multicenter clinical trial
Sign Up to like & getrecommendations! Published in 2020 at "Cancer Medicine"
DOI: 10.1002/cam4.3260
Abstract: This study aimed to compare the efficacy and toxicity of raltitrexed (Saiweijian®) plus cisplatin (SP regimen) and 5‐fluorouracil plus cisplatin (FP regimen) as concurrent chemoradiotherapy (CCRT) in patients with locally advanced nasopharyngeal carcinoma (LA‐NPC). read more here.
Keywords: advanced nasopharyngeal; versus fluorouracil; raltitrexed versus; locally advanced ... See more keywords
Chemotherapy for locoregionally advanced nasopharyngeal carcinoma: Who really needs it
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DOI: 10.1002/cam4.5497
Abstract: The CSCO and ASCO guidelines in 2021 recommend chemotherapy for stage III–IVA (8th edition of AJCC staging) nasopharyngeal carcinoma (NPC). Actually, patients with stage T3–4N0M0 are often excluded from various clinical trials of the locoregionally… read more here.
Keywords: nasopharyngeal carcinoma; advanced nasopharyngeal; locoregionally advanced; chemotherapy locoregionally ... See more keywords
Optimizing induction chemotherapy regimens for radiotherapy in patients with locoregionally advanced nasopharyngeal carcinoma
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DOI: 10.1002/cam4.5707
Abstract: The optimal number of cycles of induction chemotherapy (IC) in locoregionally advanced nasopharyngeal carcinoma (LANPC) remains unresolved. This study aimed to quantitatively assess the changes in gross tumor volumes (GTVs) and to select the most… read more here.
Keywords: advanced nasopharyngeal; induction chemotherapy; nasopharyngeal carcinoma; locoregionally advanced ... See more keywords
A multicenter, phase 3, randomized trial of concurrent chemoradiotherapy plus adjuvant chemotherapy versus radiotherapy alone in patients with regionally advanced nasopharyngeal carcinoma: 10‐year outcomes for efficacy and toxicity
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DOI: 10.1002/cncr.30850
Abstract: Concurrent‐adjuvant chemoradiotherapy (CRT) became a recommended treatment for locoregionally advanced nasopharyngeal carcinoma (NPC) with the first report of a significant survival benefit from the Intergroup 0099 study. However, data on late toxicities are lacking. Previous… read more here.
Keywords: trial; chemoradiotherapy; advanced nasopharyngeal; nasopharyngeal carcinoma ... See more keywords
NPC‐0501 trial on the value of changing chemoradiotherapy sequence, replacing 5‐fluorouracil with capecitabine, and altering fractionation for patients with advanced nasopharyngeal carcinoma
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DOI: 10.1002/cncr.32972
Abstract: A current recommendation for the treatment of patients with locoregionally advanced nasopharyngeal carcinoma (NPC) is conventional fractionated radiotherapy (RT) with concurrent cisplatin followed by adjuvant cisplatin and 5‐fluorouracil (PF). This randomized NPC‐0501 trial evaluated the… read more here.
Keywords: npc 0501; 0501 trial; sequence replacing; advanced nasopharyngeal ... See more keywords
Effects of induction chemotherapy on nutrition status in locally advanced nasopharyngeal carcinoma: a multicentre prospective study
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DOI: 10.1002/jcsm.13196
Abstract: Induction chemotherapy (IC) and concurrent chemoradiotherapy (CCRT) is the standard of care for locoregionally advanced nasopharyngeal carcinoma (LA‐NPC). This intensive treatment regimen increases acute toxicities, which could negatively impact patients' nutritional status. We conducted this… read more here.
Keywords: advanced nasopharyngeal; induction chemotherapy; nasopharyngeal carcinoma; status ... See more keywords
Combining cetuximab with chemoradiotherapy in patients with locally advanced nasopharyngeal carcinoma: A propensity score analysis.
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DOI: 10.1016/j.oraloncology.2017.02.026
Abstract: OBJECTIVE To compare the effectiveness of concurrent cisplatin chemoradiotherapy plus cetuximab with that of concurrent chemoradiotherapy (CCRT) alone in locoregionally advanced nasopharyngeal carcinoma (LRANPC) patients. MATERIALS AND METHODS A total of 3257 LRANPC patients from… read more here.
Keywords: advanced nasopharyngeal; propensity score; chemoradiotherapy; cetuximab ... See more keywords
Prognostic Nomogram For Locoregionally Advanced Nasopharyngeal Carcinoma
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DOI: 10.1038/s41598-020-57968-x
Abstract: The TNM staging system of NPC is the most important model for survival prediction. However, this model does not consider the biological variability of the tumor itself. This study aimed to develop a nomogram for… read more here.
Keywords: carcinoma; system; prognostic nomogram; advanced nasopharyngeal ... See more keywords
Treatment outcomes of induction chemotherapy combined with intensity-modulated radiotherapy and adjuvant chemotherapy for locoregionally advanced nasopharyngeal carcinoma in Southeast China
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DOI: 10.1097/md.0000000000027023
Abstract: Abstract Induction chemotherapy (IC) and adjuvant chemotherapy (AC) are used to enhance tumor locoregional control and support early treatment for distant metastases. However, optimum combinatorial treatment of these chemoradiotherapy regimens with radiotherapy in curing locoregionally… read more here.
Keywords: chemotherapy; treatment; induction chemotherapy; locoregionally advanced ... See more keywords
Induction chemotherapy with sequential nimotuzumab plus concurrent chemoradiotherapy in advanced nasopharyngeal carcinoma: A retrospective real-world study
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DOI: 10.1097/md.0000000000032732
Abstract: Many locally advanced nasopharyngeal carcinoma patients develop local recurrence or distant metastasis. Our retrospective real-world study aims to evaluate the efficacy and safety of curative sequential approach with induction chemotherapy followed by concurrent chemoradiation + nimotuzumab as… read more here.
Keywords: advanced nasopharyngeal; nasopharyngeal carcinoma; induction chemotherapy; group ... See more keywords