ALK Gene Mutation and ALK Protein Expression in Advanced Neuroblastoma and the Potential Value in Risk Stratification in Fine-Needle Aspiration Biopsy Samples.
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DOI: 10.1093/ajcp/aqac172
Abstract: OBJECTIVES The protein ALK is targeted for therapy in neuroblastoma, and ALK mutation confers a poor prognosis. We evaluated ALK in a cohort of patients with advanced neuroblastoma diagnosed by fine-needle aspiration biopsy (FNAB). METHODS… read more here.
Keywords: advanced neuroblastoma; expression; alk gene; mutation ... See more keywords
Immune landscape and in vivo immunogenicity of NY-ESO-1 tumor antigen in advanced neuroblastoma patients
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DOI: 10.1186/s12885-018-4910-8
Abstract: BackgroundIndirect evidence suggesting the immunosensitivity/immunogenicity of neuroblastoma is accumulating. The aims of this study were to investigate the immune landscape of neuroblastoma and to evaluate the in vivo immunogenicity of the NY-ESO-1 tumor antigen in… read more here.
Keywords: immunogenicity; immunogenicity eso; neuroblastoma patients; antigen ... See more keywords