Effect of a MUC5AC Antibody (NPC-1C) Administered With Second-Line Gemcitabine and Nab-Paclitaxel on the Survival of Patients With Advanced Pancreatic Ductal Adenocarcinoma
Sign Up to like & getrecommendations! Published in 2023 at "JAMA Network Open"
DOI: 10.1001/jamanetworkopen.2022.49720
Abstract: Key Points Question Does targeting MUC5AC with the NPC-1C antibody augment the antitumor activity of gemcitabine plus nab-paclitaxel as a second-line treatment for pancreatic cancer? Findings In this randomized phase 2 trial of 78 patients… read more here.
Keywords: nab paclitaxel; advanced pancreatic; line; line gemcitabine ... See more keywords
Pretreatment values of bilirubin and albumin are not prognostic predictors in patients with advanced pancreatic cancer
Sign Up to like & getrecommendations! Published in 2018 at "Cancer Medicine"
DOI: 10.1002/cam4.1848
Abstract: To identify the pretreatment values of bilirubin and albumin and other serum biomarkers in predicting the prognosis for advanced pancreatic cancer. read more here.
Keywords: advanced pancreatic; bilirubin albumin; pancreatic cancer; values bilirubin ... See more keywords
Effect of S‐1 on survival outcomes in 838 patients with advanced pancreatic cancer: A 7‐year multicenter observational cohort study in Taiwan
Sign Up to like & getrecommendations! Published in 2019 at "Cancer Medicine"
DOI: 10.1002/cam4.2094
Abstract: Studies have rarely explored the efficacy of S‐1 in treating advanced pancreatic cancer outside Japan. This study compared the survival outcomes of patients with advanced pancreatic cancer treated with S‐1 with the survival outcomes of… read more here.
Keywords: patients advanced; survival outcomes; advanced pancreatic; pancreatic cancer ... See more keywords
Stereotactic body radiotherapy vs conventionally fractionated chemoradiation in locally advanced pancreatic cancer: A multicenter case‐control study (PAULA‐1)
Sign Up to like & getrecommendations! Published in 2020 at "Cancer Medicine"
DOI: 10.1002/cam4.3330
Abstract: Conventionally fractionated chemoradiation (CRT) or chemotherapy (CHT) are considered as standard options in locally advanced pancreatic cancer (LAPC) while stereotactic body radiotherapy (SBRT) is an emerging treatment in this setting. The aim of this study… read more here.
Keywords: conventionally fractionated; advanced pancreatic; pancreatic cancer; cancer ... See more keywords
Neoadjuvant chemotherapy and radiotherapy outcomes in borderline‐resectable and locally‐advanced pancreatic cancer patients
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DOI: 10.1002/cam4.5523
Abstract: There is no agreed upon standard of care for borderline‐resectable pancreatic cancer (BRPC) or locally‐advanced pancreatic cancer (LAPC) patients regarding the benefit of chemotherapy or radiation alone or in combination. read more here.
Keywords: locally advanced; neoadjuvant chemotherapy; pancreatic cancer; borderline resectable ... See more keywords
Efficacy and safety of 177Lu‑DOTATATE in patients with advanced pancreatic neuroendocrine tumours: data from the NETTER-R international, retrospective study
Sign Up to like & getrecommendations! Published in 2022 at "European Journal of Nuclear Medicine and Molecular Imaging"
DOI: 10.1007/s00259-022-05771-3
Abstract: NETTER-R aimed to determine the efficacy, safety and tolerability of 177Lu-DOTATATE in patients with progressive, advanced pancreatic neuroendocrine tumours (panNETs) using retrospective real-world data from multiple sites. This international study retrospectively included patients with panNETs… read more here.
Keywords: dotatate; efficacy safety; dotatate patients; 177lu dotatate ... See more keywords
Prognostic Scoring System for Patients Who Present with a Gastric Outlet Obstruction Caused by Advanced Pancreatic Adenocarcinoma
Sign Up to like & getrecommendations! Published in 2017 at "World Journal of Surgery"
DOI: 10.1007/s00268-017-4027-2
Abstract: BackgroundGastroenterostomy and stent placement are the most common palliative procedures for patients with a gastric outlet obstruction caused by advanced pancreatic adenocarcinoma. Gastroenterostomy is regarded as the optimum treatment for patients in whom a longer… read more here.
Keywords: caused advanced; advanced pancreatic; pancreatic adenocarcinoma; obstruction caused ... See more keywords
Nab-paclitaxel plus S-1 as first-line followed by S-1 maintenance for advanced pancreatic adenocarcinoma: a single-arm phase II trial
Sign Up to like & getrecommendations! Published in 2018 at "Cancer Chemotherapy and Pharmacology"
DOI: 10.1007/s00280-018-3650-4
Abstract: PurposeWe conducted a single-arm prospective phase II study to determine the efficacy and safety of the first-line treatment of advanced pancreatic cancer with nab-paclitaxel and S-1 followed by S-1 maintenance therapy.MethodsNab-paclitaxel was administered intravenously on… read more here.
Keywords: first line; maintenance; advanced pancreatic; single arm ... See more keywords
Distal Pancreatectomy with Celiac Axis Resection—with Posterior Ramps Approach—for Locally Advanced Pancreatic Adenocarcinoma with Celiac Trunk Infiltration (Modified Appleby Procedure) (with Video)
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Gastrointestinal Surgery"
DOI: 10.1007/s11605-020-04782-5
Abstract: With the advent of FOLFIRINOX and neoadjuvant radiotherapy, the surgical indications for adenocarcinoma have expanded. Locally advanced pancreatic adenocarcinomas of the body/tail with infiltration of the celiac trunk which have a good clinical, biological, and… read more here.
Keywords: celiac trunk; advanced pancreatic; procedure; celiac ... See more keywords
Intraoperative electrochemotherapy in locally advanced pancreatic cancer: indications, techniques and results—a single-center experience
Sign Up to like & getrecommendations! Published in 2020 at "Updates in Surgery"
DOI: 10.1007/s13304-020-00782-x
Abstract: Background Locally advanced pancreatic cancer (LAPC) is usually treated with chemoradiotherapy with poor results. The aim of the study was to assess whether intraoperative electrochemotherapy could be proposed as additional therapy in treating LAPC. Methods… read more here.
Keywords: advanced pancreatic; pancreatic cancer; electrochemotherapy; intraoperative electrochemotherapy ... See more keywords
[Stereotactic body radiotherapy for locally advanced pancreatic cancer: A systemic review].
Sign Up to like & getrecommendations! Published in 2021 at "Cancer radiotherapie : journal de la Societe francaise de radiotherapie oncologique"
DOI: 10.1016/j.canrad.2020.08.047
Abstract: Stereotactic body radiation therapy (SBRT) for locally advanced pancreatic cancer (LAPC) is an emerging treatment option. Most studies showed local control of approximately 75% with no evidence of improved overall survival. Gastrointestinal toxicities could be… read more here.
Keywords: advanced pancreatic; pancreatic cancer; stereotactic body; systemic review ... See more keywords