LCIG in treatment of non‐motor symptoms in advanced Parkinson’s disease: Review of literature
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DOI: 10.1002/brb3.1757
Abstract: For managing nonmotor symptoms (NMS) in advanced Parkinson's disease (PD), levodopa–carbidopa intestinal gel (LCIG) infusion is of interest as it shows lesser plasma fluctuations of both drugs as compared to oral levodopa–carbidopa (LC). read more here.
Keywords: treatment non; non motor; lcig treatment; parkinson disease ... See more keywords
Problems related to levodopa‐carbidopa intestinal gel treatment in advanced Parkinson's disease
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DOI: 10.1002/brb3.737
Abstract: Continuous levodopa‐carbidopa intestinal gel (LCIG) diminishes daily “off” time and dyskinesia in patients with advanced Parkinson′s disease (PD). Complications are common with percutaneous endoscopic gastrostomy with a jejunal extension tube (PEG‐J). read more here.
Keywords: levodopa carbidopa; carbidopa intestinal; parkinson disease; advanced parkinson ... See more keywords
The Cost Effectiveness of Levodopa-Carbidopa Intestinal Gel in the Treatment of Advanced Parkinson’s Disease in England
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DOI: 10.1007/s40273-022-01132-y
Abstract: Parkinson’s disease is a progressive neurodegenerative disease, which significantly impacts patients’ quality of life and is associated with high treatment and direct healthcare costs. In England, levodopa/carbidopa intestinal gel (LCIG) is indicated for the treatment… read more here.
Keywords: cost effectiveness; disease; parkinson disease; advanced parkinson ... See more keywords
Neurologists’ preferences for device-aided therapy for advanced Parkinson’s disease in Japan
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DOI: 10.1080/03007995.2022.2129800
Abstract: Abstract Objective This study measures the relative preference for attributes of device-aided therapies (DATs) for advanced Parkinson’s Disease (PD) from the perspective of Japanese neurologists. Methods Attributes and levels were elicited based on literature and… read more here.
Keywords: device aided; parkinson disease; device; advanced parkinson ... See more keywords
The use of enteral access for continuous delivery of levodopa-carbidopa in patients with advanced Parkinson’s disease
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DOI: 10.1177/2050640616650804
Abstract: Background Continuous delivery to the jejunum of levodopa-carbidopa is a promising therapy in patients with advanced Parkinson’s disease, as it reduces motor fluctuation. Percutaneous endoscopic gastrostomy and jejunal tube (PEG-J) placement is a suitable option… read more here.
Keywords: levodopa carbidopa; disease; adverse events; patients advanced ... See more keywords
Criteria for identification of advanced Parkinson’s disease: the results of the Italian subgroup of OBSERVE-PD observational study
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DOI: 10.1186/s12883-022-02554-z
Abstract: Background Frequency of Advanced Parkinson’s Disease (APD) and its clinical characteristics are still not well defined. Here, we aimed to assess APD prevalence in the Italian OBSERVE-PD cohort, as well as treatment eligibility to device-aided… read more here.
Keywords: study; judgment; parkinson disease; advanced parkinson ... See more keywords
Changes in elbow flexion EMG morphology during adjustment of deep brain stimulator in advanced Parkinson’s disease
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DOI: 10.1371/journal.pone.0266936
Abstract: Objective Deep brain stimulation (DBS) is an effective treatment for motor symptoms of advanced Parkinson’s disease (PD). Currently, DBS programming outcome is based on a clinical assessment. In an optimal situation, an objectively measurable feature… read more here.
Keywords: parkinson disease; dbs; adjustment; advanced parkinson ... See more keywords
Impact of Supporting People with Advanced Parkinson’s Disease on Carer’s Quality of Life and Burden
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DOI: 10.2147/ndt.s256217
Abstract: Purpose The aim of this study was to assess the burden and the quality of life (QoL) perceived by caregivers assisting advanced Parkinson’s disease (PD) patients. Patients and Methods Consecutive advanced PD patients treated with… read more here.
Keywords: quality life; parkinson disease; advanced parkinson; care partners ... See more keywords
3T MRI-SWI based volumetric analysis of the subthalamic and red nuclei in advanced Parkinson's disease.
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DOI: 10.23736/s0390-5616.20.04935-8
Abstract: BACKGROUND Parkinson's disease (PD) is a neurodegenerative disease mainly involving the dopaminergic neurons of the substantia nigra. The subthalamic nucleus (STN) also plays an important role in the disease process and now is an important… read more here.
Keywords: parkinson disease; advanced parkinson; mri swi; stn volumes ... See more keywords
Management of advanced Parkinson’s disease in Israel: Clinicians viewpoint and action items
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Aging Neuroscience"
DOI: 10.3389/fnagi.2022.1029824
Abstract: Parkinson’s disease (PD) is taking a staggering toll on healthcare systems worldwide, with the bulk of the expenditures invested in the late stages of the disease. Considering the rising life expectancy and the increasing prevalence… read more here.
Keywords: disease; parkinson disease; management advanced; management ... See more keywords
Characterisation of advanced Parkinson's disease: OBSERVE-PD observational study - results of the Swiss subgroup.
Sign Up to like & getrecommendations! Published in 2021 at "Swiss medical weekly"
DOI: 10.4414/smw.2021.20419
Abstract: AIMS OF THE STUDY Currently, the characterisation of advanced Parkinson’s disease (APD) does not follow standardised diagnostic criteria, which complicates the evaluation of ongoing care and treatment strategies, such as eligibility for device-aided treatment (DAT).… read more here.
Keywords: study; apd; parkinson disease; advanced parkinson ... See more keywords