Real-World Outcomes of Pazopanib Treatment in Korean Patients with Advanced Soft Tissue Sarcoma: A Multicenter Retrospective Cohort Study
Sign Up to like & getrecommendations! Published in 2020 at "Targeted Oncology"
DOI: 10.1007/s11523-020-00731-z
Abstract: Background Pazopanib is the only tyrosine kinase inhibitor approved for the treatment of patients with advanced soft tissue sarcoma (STS) who have received prior chemotherapy, but there have been limited real-world data on pazopanib for… read more here.
Keywords: sarcoma; real world; advanced soft; treatment ... See more keywords
Effect of the hot rolling on Goss development and magnetic induction in an advanced soft magnetic Fe–27%Co alloy
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Alloys and Compounds"
DOI: 10.1016/j.jallcom.2020.155149
Abstract: Abstract This paper shows a complete study about the characterization of the texture and the microstructure evolution of an industrial thermo-mechanical processing aiming to develop an advanced soft magnetic Fe–27%Co material with a sharp Goss… read more here.
Keywords: alloy; goss; advanced soft; soft magnetic ... See more keywords
Advanced soft robot modeling in ChainQueen
Sign Up to like & getrecommendations! Published in 2021 at "Robotica"
DOI: 10.1017/s0263574721000722
Abstract: We present extensions to ChainQueen, an open source, fully differentiable material point method simulator for soft robotics. Previous work established ChainQueen as a powerful tool for inference, control, and co-design for soft robotics. We detail… read more here.
Keywords: modeling chainqueen; soft robot; advanced soft; robotics ... See more keywords
PP147 Olaratumab With Doxorubicin For Advanced Soft Tissue Sarcoma
Sign Up to like & getrecommendations! Published in 2018 at "International Journal of Technology Assessment in Health Care"
DOI: 10.1017/s0266462318002775
Abstract: Introduction: The National Institute for Health and Care Excellence (NICE) invited the manufacturer of olaratumab (Lartruvo®), Eli Lilly & Company Limited, to submit evidence for the clinical and cost effectiveness of this drug, in combination… read more here.
Keywords: advanced soft; soft tissue; cost; doxorubicin advanced ... See more keywords
Newer medical therapies for metastatic soft tissue sarcoma
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DOI: 10.1080/14737140.2017.1285229
Abstract: ABSTRACT Introduction: Metastatic/advanced soft tissue sarcoma has a poor prognosis conventionally, treatment options have been limited. In recent years, this area has been a rich ground for research with many new drugs being approved and… read more here.
Keywords: treatment options; advanced soft; tissue sarcoma; soft tissue ... See more keywords
Phase Ib/II Study of the Safety and Efficacy of Combination Therapy with Multikinase VEGF Inhibitor Pazopanib and MEK Inhibitor Trametinib In Advanced Soft Tissue Sarcoma
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DOI: 10.1158/1078-0432.ccr-17-0272
Abstract: Purpose: Pazopanib, a multireceptor tyrosine kinase inhibitor targeting primarily VEGFRs1–3, is approved for advanced soft tissue sarcoma (STS) and renal cell cancer. Downstream of VEGFR, trametinib is an FDA-approved MEK inhibitor used for melanoma. We… read more here.
Keywords: pazopanib; combination; inhibitor; advanced soft ... See more keywords
The real-life outcome of pazopanib in patients with advanced soft tissue sarcoma: A retrospective cross-sectional study of a Turkish cohort
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Oncology Pharmacy Practice"
DOI: 10.1177/1078155220904138
Abstract: Introduction Soft tissue sarcomas are a heterogeneous and rare group of cancers with a short median overall survival despite the chemotherapy. Pazopanib has approval for the treatment of advanced soft tissue sarcoma. We aimed to… read more here.
Keywords: pazopanib; tissue sarcoma; advanced soft; soft tissue ... See more keywords
Safety and efficacy of Pazopanib in advanced soft tissue sarcoma: PALETTE (EORTC 62072) subgroup analyses
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DOI: 10.1186/s12885-019-5988-3
Abstract: BackgroundPALETTE is a phase 3 trial that demonstrated single-agent activity of pazopanib in advanced soft tissue sarcomas (aSTS). We performed retrospective subgroup analyses to explore potential relationships between patient characteristics, prior lines of therapy, dose… read more here.
Keywords: pazopanib; advanced soft; efficacy; subgroup analyses ... See more keywords
Response of advanced soft tissue sarcoma to apatinib: A retrospective analysis.
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Clinical Oncology"
DOI: 10.1200/jco.2017.35.15_suppl.e22502
Abstract: e22502Background: Soft tissue sarcomas (STSs) are rare but malignant tumors with high risks of local recurrence and distant metastasis. Promising efficacy of apatinib was reported in several subtyp... read more here.
Keywords: sarcoma apatinib; tissue sarcoma; advanced soft; soft tissue ... See more keywords
Developments in the management of advanced soft-tissue sarcoma – olaratumab in context
Sign Up to like & getrecommendations! Published in 2018 at "OncoTargets and therapy"
DOI: 10.2147/ott.s127609
Abstract: Lartruvo® (olaratumab) is a fully human immunoglobulin G subclass 1 (IgG1) monoclonal antibody that inhibits platelet-derived growth factor receptor alpha (PDGFRα). The antitumor activity of olaratumab has been tested in vitro and in vivo, and… read more here.
Keywords: management advanced; developments management; tissue sarcoma; advanced soft ... See more keywords
A review of the efficacy of trabectedin as second-line treatment of advanced soft tissue sarcoma.
Sign Up to like & getrecommendations! Published in 2022 at "Future oncology"
DOI: 10.2217/fon-2022-0517
Abstract: The goal of second-line therapy for most patients with advanced soft tissue sarcoma is long-term tumor control without detriment to quality of life. Clinical practice guidelines recommend trabectedin as a second-line option for advanced soft… read more here.
Keywords: advanced soft; soft tissue; tissue sarcoma; line ... See more keywords