Frequent Missed Opportunities for Earlier Diagnosis of Advanced-Stage Colorectal or Lung Cancer.
Sign Up to like & getrecommendations! Published in 2025 at "JAMA internal medicine"
DOI: 10.1001/jamainternmed.2025.2875
Abstract: Importance Missed and delayed cancer diagnoses worsen patient outcomes. Overlooking cancer-related diagnostic signals may result in advanced-stage presentations. Objective To develop and implement a digital quality measure of the proportion of advanced-stage cancer diagnoses in… read more here.
Keywords: cancer; health system; missed opportunities; advanced stage ... See more keywords
Association of Primary Treatment Modality for Advanced-Stage Oropharyngeal Squamous Cell Carcinoma With Survival Outcomes
Sign Up to like & getrecommendations! Published in 2021 at "JAMA Network Open"
DOI: 10.1001/jamanetworkopen.2021.12067
Abstract: This comparative effectiveness research investigates survival outcomes for chemoradiotherapy vs surgical treatment among patients with advanced-stage oropharyngeal squamous cell carcinoma. read more here.
Keywords: stage oropharyngeal; survival outcomes; squamous cell; cell carcinoma ... See more keywords
PARP Inhibitor Maintenance After First-Line Chemotherapy in Advanced-Stage Epithelial Ovarian Cancer
Sign Up to like & getrecommendations! Published in 2025 at "JAMA Network Open"
DOI: 10.1001/jamanetworkopen.2025.41648
Abstract: This systematic review and meta-analysis investigates the association of first-line poly(adenosine diphosphate-ribose) polymerase inhibitor (PARP inhibitor) maintenance therapy with efficacy and safety outcomes among patients with advanced-stage epithelial ovarian cancer. read more here.
Keywords: parp inhibitor; stage epithelial; first line; inhibitor ... See more keywords
Targeted O‐glycoproteomics explored increased sialylation and identified MUC16 as a poor prognosis biomarker in advanced‐stage bladder tumours
Sign Up to like & getrecommendations! Published in 2017 at "Molecular Oncology"
DOI: 10.1002/1878-0261.12035
Abstract: Bladder carcinogenesis and tumour progression is accompanied by profound alterations in protein glycosylation on the cell surface, which may be explored for improving disease management. In a search for prognosis biomarkers and novel therapeutic targets… read more here.
Keywords: poor prognosis; bladder; bladder tumours; advanced stage ... See more keywords
In silico DNA methylation analysis identifies potential prognostic biomarkers in type 2 papillary renal cell carcinoma
Sign Up to like & getrecommendations! Published in 2019 at "Cancer Medicine"
DOI: 10.1002/cam4.2402
Abstract: There are currently no effective treatments for advanced‐stage papillary renal cell carcinoma (PRCC). The goal of this study is to define potential DNA methylation‐based markers and treatment targets for advanced‐stage type 2 PRCC. Progressive DNA… read more here.
Keywords: type prcc; methylation; advanced stage; stage type ... See more keywords
Efficacy of escalating therapy with brentuximab vedotin‐AVD in advanced stage Hodgkin lymphoma patients with positive interim positron emission tomography after ABVD
Sign Up to like & getrecommendations! Published in 2024 at "Hematological Oncology"
DOI: 10.1002/hon.3299
Abstract: Patients with advanced‐stage Hodgkin lymphoma treated with ABVD who have a positive interim FDG‐PET (iPET) have a poor prognosis. Escalation to BEACOPP has been shown to improve progression‐free survival (PFS). However, randomized trials are lacking… read more here.
Keywords: positive interim; therapy; stage hodgkin; advanced stage ... See more keywords
Defining and Addressing the Current Unmet Medical Needs for the Frontline Treatment of Advanced Stage Aggressive Large B‐Cell Lymphoma: A Perspective From an Ad Hoc Panel of Italian Experts
Sign Up to like & getrecommendations! Published in 2025 at "Hematological Oncology"
DOI: 10.1002/hon.70152
Abstract: Aggressive large B‐cell lymphomas (LBCL) include a range of disease types characterized by heterogenous histopathologic, molecular, and genetic features. In this review, we summarize the main standardized disease assessments, treatments and patient journey and we… read more here.
Keywords: panel; treatment; advanced stage; large cell ... See more keywords
Muscle loss during primary debulking surgery and chemotherapy predicts poor survival in advanced‐stage ovarian cancer
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Cachexia, Sarcopenia and Muscle"
DOI: 10.1002/jcsm.12524
Abstract: Sarcopenia is commonly observed in patients with advanced‐stage epithelial ovarian cancer (EOC). However, the effect of body composition changes—during primary debulking surgery (PDS) and adjuvant platinum‐based chemotherapy—on outcomes of patients with advanced‐stage EOC is unknown.… read more here.
Keywords: debulking surgery; ovarian cancer; advanced stage; primary debulking ... See more keywords
Advanced stage primary mucinous ovarian carcinoma. Where do we stand ?
Sign Up to like & getrecommendations! Published in 2020 at "Archives of Gynecology and Obstetrics"
DOI: 10.1007/s00404-020-05489-3
Abstract: Objective To evaluate factors associated with survival of patients with advanced stage mucinous ovarian carcinoma (MOC) using a large multi-institutional database. Methods Patients diagnosed between 2004 and 2014 with advanced stage (III–IV) MOC were identified… read more here.
Keywords: mucinous ovarian; advanced stage; stage primary; stage ... See more keywords
Analysis of dysphagia in advanced-stage head-and-neck cancer patients: impact on quality of life and development of a preventive swallowing treatment
Sign Up to like & getrecommendations! Published in 2018 at "European Archives of Oto-Rhino-Laryngology"
DOI: 10.1007/s00405-018-5054-9
Abstract: ObjectivesSwallowing and voice dysfunctions are common side effects following head-and-neck squamous-cell carcinoma (HNSCC) treatment. Our aim was to analyze the relationships between quality of life, swallowing, and phonatory problems in patients with an advanced-stage HNSCC… read more here.
Keywords: treatment; dysphagia; advanced stage; quality life ... See more keywords
Prevalence of obstructive sleep apnea after treatment for advanced T-stage head and neck cancer
Sign Up to like & getrecommendations! Published in 2024 at "European Archives of Oto-Rhino-Laryngology"
DOI: 10.1007/s00405-024-08467-6
Abstract: Treatment of head and neck cancer (HNC) may lead to obstructive sleep apnea (OSA), but conclusive results on the prevalence of OSA are lacking. The objective of this study is to investigate the prevalence of… read more here.
Keywords: cancer; treatment; stage; neck ... See more keywords