Coronavirus Disease 2019 and Management of Advanced Therapies in Parkinson's Disease; Peculiar Needs for Deep Brain Stimulation Patients?
Sign Up to like & getrecommendations! Published in 2020 at "Movement Disorders Clinical Practice"
DOI: 10.1002/mdc3.13033
Abstract: We considered the review by Fasano and colleagues a stimulating document. The article defines a decisional algorithm on advanced therapies of Parkinson’s Diseases (PD) and addresses the clinical needs caused by the severe acute respiratory… read more here.
Keywords: intervention; disease 2019; disease; advanced therapies ... See more keywords
Treatment patterns, unmet need, and impact on patient-reported outcomes of psoriatic arthritis in the United States and Europe
Sign Up to like & getrecommendations! Published in 2018 at "Rheumatology International"
DOI: 10.1007/s00296-018-4195-x
Abstract: Psoriatic arthritis (PsA) is a chronic, inflammatory disease. The effects of PsA real-world treatment patterns on patient-reported outcomes in the US and 5 European countries (EU5; France, Germany, Italy, Spain, UK) were evaluated. Respondents from… read more here.
Keywords: psoriatic arthritis; patient reported; treatment; advanced therapies ... See more keywords
Advanced Therapies for Inflammatory Bowel Disease: Navigating Payor and Financial Challenges
Sign Up to like & getrecommendations! Published in 2024 at "Current Gastroenterology Reports"
DOI: 10.1007/s11894-024-00916-w
Abstract: In the United Sates the cost of managing Crohn’s disease and ulcerative colitis, the two most common inflammatory bowel diseases, is a major factor that can alter the course of treatment. The increasing use of… read more here.
Keywords: therapies inflammatory; navigating payor; advanced therapies; bowel disease ... See more keywords
Costs and Treatment Patterns Among Patients with Atopic Dermatitis Using Advanced Therapies in the United States: Analysis of a Retrospective Claims Database
Sign Up to like & getrecommendations! Published in 2020 at "Dermatology and Therapy"
DOI: 10.1007/s13555-020-00413-8
Abstract: Introduction For many, atopic dermatitis (AD) is not adequately controlled with topical regimens. This analysis examined treatment using advanced therapies and associated costs. Methods The IQVIA Health Plan Claims data set was analyzed. Patients aged ≥ 12 years… read more here.
Keywords: therapy; index date; treatment; advanced therapies ... See more keywords
A Comparison of Surgeon's Subjective Assessment of Frailty to Formal Frailty Testing in Patients with Heart Failure Being Evaluated for Advanced Therapies
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Cardiac Failure"
DOI: 10.1016/j.cardfail.2019.07.467
Abstract: Introduction Most heart failure (HF) programs use a subjective provider assessment (SPA) of frailty, or “eye-ball” test, for patient selection for advanced therapies (AT). The Modified Fried Frailty Index (mFFI) is an objective assessment of… read more here.
Keywords: assessment; advanced therapies; frailty; assessment frailty ... See more keywords
The phenotype of gingival fibroblasts and their potential use in advanced therapies.
Sign Up to like & getrecommendations! Published in 2020 at "European journal of cell biology"
DOI: 10.1016/j.ejcb.2020.151123
Abstract: Advanced therapies in medicine use stem cells, gene editing, and tissues to treat a wide range of conditions. One of their goals is to stimulate endogenous repair of tissues and organs by manipulating stem cells… read more here.
Keywords: medicine; phenotype gingival; fibroblasts potential; gingival fibroblasts ... See more keywords
Delivering advanced therapies: the big pharma approach
Sign Up to like & getrecommendations! Published in 2017 at "Gene Therapy"
DOI: 10.1038/gt.2017.65
Abstract: After two decades of focused development and some recent clinical successes, cell and gene therapy (CGT) is emerging as a promising approach to personalized medicines. Genetically engineered cells as a medical modality are poised to… read more here.
Keywords: delivering advanced; big pharma; therapies big; pharma approach ... See more keywords
Use of exosomes as vectors to carry advanced therapies
Sign Up to like & getrecommendations! Published in 2020 at "RSC Advances"
DOI: 10.1039/d0ra02414g
Abstract: Exosomes are microvesicles of nanometric size involved in the communication between cells and tissues. Inside their bilipidic membrane they carry nucleic acids such as cargos (DNA, miRNA, etc.). Some of the advantages that make exosomes… read more here.
Keywords: use exosomes; exosomes vectors; vectors carry; carry advanced ... See more keywords
Nanostructured particles assembled from natural building blocks for advanced therapies.
Sign Up to like & getrecommendations! Published in 2022 at "Chemical Society reviews"
DOI: 10.1039/d1cs00343g
Abstract: Advanced treatments based on immune system manipulation, gene transcription and regulation, specific organ and cell targeting, and/or photon energy conversion have emerged as promising therapeutic strategies against a range of challenging diseases. Naturally derived macromolecules… read more here.
Keywords: advanced therapies; therapy; natural building; building blocks ... See more keywords
Comparative Efficacy of Advanced Therapies for Management of Moderate-to-Severe Crohn's Disease: 2025 AGA Evidence Synthesis.
Sign Up to like & getrecommendations! Published in 2025 at "Gastroenterology"
DOI: 10.1053/j.gastro.2025.08.032
Abstract: BACKGROUND & AIMS We performed an updated systematic review and network meta-analysis to inform the 2025 American Gastroenterological Association Clinical Guidelines on the management of moderate-to-severe Crohn's disease (CD). METHODS We searched multiple electronic databases… read more here.
Keywords: moderate severe; evidence supported; advanced therapies; certainty evidence ... See more keywords
The incidence of remission and indicators of inadequate response to advanced therapy in patients with ulcerative colitis: results from medical charts in the United Kingdom
Sign Up to like & getrecommendations! Published in 2023 at "Current Medical Research and Opinion"
DOI: 10.1080/03007995.2023.2194782
Abstract: Abstract Objective A considerable proportion of patients with moderate-to-severe ulcerative colitis (UC) treated with advanced therapies do not achieve remission, even after 1 year of treatment, and suboptimal response to advanced therapies is frequently observed… read more here.
Keywords: inadequate response; advanced therapies; remission; therapy ... See more keywords