Second‐line treatment options in advanced thymic carcinoma after failure of platinum‐based chemotherapy: A multicenter retrospective study
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DOI: 10.1002/cam4.5053
Abstract: Currently there is no standard therapy recommended for second‐line treatment for thymic carcinoma. Our study compared multidrug chemotherapy, single‐agent chemotherapy, and PD‐1 inhibitors in patients diagnosed with advanced thymic carcinoma who had previous platinum‐based chemotherapy… read more here.
Keywords: advanced thymic; thymic carcinoma; line treatment; second line ... See more keywords
Advanced thymic lymphoepithelioma-like carcinoma with bone marrow metastases treated by immunotherapy combined with antiangiogenesis therapy: a case report
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DOI: 10.1097/cad.0000000000001293
Abstract: Thymic lymphoepithelioma-like carcinoma (LELC) is a rare primary malignant neoplasm originating from the thymus. Thymic LELC diagnosis is often terminal when diagnosed, some patients have lost the opportunity for surgery. Platinum- and anthracycline-based systemic chemotherapy… read more here.
Keywords: advanced thymic; bone marrow; therapy; case ... See more keywords
Impact of PD‐L1, transforming growth factor‐β expression and tumor‐infiltrating CD8+ T cells on clinical outcome of patients with advanced thymic epithelial tumors
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DOI: 10.1111/1759-7714.12826
Abstract: Advanced thymic epithelial tumors (TETs) are indolent and poorly responsive to chemotherapy. PD‐1/PD‐L1 inhibitors have shown remarkable clinical benefit in several cancers; however, many immunomodulatory molecules have been identified that affect the immune response. This… read more here.
Keywords: transforming growth; advanced thymic; growth factor; tumor infiltrating ... See more keywords
Phase II study of S‐1 plus cisplatin with concurrent radiotherapy for locally advanced thymic carcinoma: Results of the LOGIK1605/JART‐1501 study
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DOI: 10.1111/1759-7714.14586
Abstract: Combination chemotherapy is used to treat advanced thymic carcinoma; however, the effects are insufficient. read more here.
Keywords: study plus; advanced thymic; thymic carcinoma; phase study ... See more keywords
Outcomes of extended surgical resections for locally advanced thymic malignancies: a narrative review.
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DOI: 10.21037/gs-21-642
Abstract: Background and Objective Thymic malignancies represent the most common anterior mediastinal neoplasms, as well as rare and challenging tumors. Surgery is the cornerstone in the treatment of thymic malignancies, although a multidisciplinary approach is mandatory,… read more here.
Keywords: locally advanced; narrative review; advanced thymic; thymic malignancies ... See more keywords
Robotic thymectomy for advanced thymic epithelial tumor: indications and technical aspects.
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DOI: 10.21037/jtd.2019.09.27
Abstract: Robotic thymectomy is widely accepted as a valuable treatment option for surgical resection of thymic epithelial tumor as minimally invasive surgery has shown better early clinical outcomes than open surgery. Technical advances in robotic surgery… read more here.
Keywords: advanced thymic; thymic epithelial; robotic thymectomy; epithelial tumor ... See more keywords
The role of surgery in advanced thymic tumors: A retrospective cohort study
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DOI: 10.3389/fonc.2022.1073641
Abstract: Background There is no definitive and detailed treatment guideline for advanced thymic tumors, thus when lymph node and other organ metastasis are present, clinical guidelines recommend chemotherapy-based multidisciplinary treatment. A consensus has been reached that… read more here.
Keywords: advanced thymic; surgery; thymic tumors; thymic carcinoma ... See more keywords