Recent advancements in the medicinal chemistry of bacterial type II topoisomerase inhibitors.
Sign Up to like & getrecommendations! Published in 2020 at "Bioorganic chemistry"
DOI: 10.1016/j.bioorg.2020.104266
Abstract: Replication proteins are sought as a potential targets for antimicrobial agents. Despite their promising target characteristics, only topoisomerase II inhibitors targeting DNA gyrase and/or topoisomerase IV have reached clinical use. Topoisomerases are the enzymes that… read more here.
Keywords: topoisomerase inhibitors; medicinal chemistry; chemistry; recent advancements ... See more keywords