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Published in 2018 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-8651-4_3
Abstract: Spinal muscular atrophy (SMA) is an autosomal recessive disorder caused by a mutation in SMN1 that stops production of SMN (survival of motor neuron) protein. Insufficient levels of SMN results in the loss of motor…
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advances clinical;
spinal muscular;
recent advances;
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Published in 2025 at "Current Cardiology Reports"
DOI: 10.1007/s11886-025-02243-6
Abstract: We sought to review the various intracoronary imaging modalities (intravascular ultrasound, optical coherence tomography, and near-infrared spectroscopy) and the latest evidence supporting their use in clinical practice. There is an increasing body of evidence that…
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advances clinical;
coronary imaging;
imaging update;
imaging ... See more keywords
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Published in 2017 at "Current opinion in biotechnology"
DOI: 10.1016/j.copbio.2017.01.002
Abstract: The use of novel materials in the nano-scale size range for applications in devices, drugs and diagnostic agents comes with a number of new opportunities, and also serious challenges to human applications. The larger size…
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advances clinical;
use;
translation nanotechnology;
pharmacology ... See more keywords
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Published in 2017 at "Seminars in immunology"
DOI: 10.1016/j.smim.2017.08.007
Abstract: The LTB4 pathway is an attractive target for therapeutic drug development. Two broad classes of drugs have been pursued: antagonists of the primary LTB4 receptors (BLT1 and BLT2) and inhibitors of LTA4 Hydrolase (LTA4H), the…
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pathway drugs;
advances clinical;
pathway;
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Published in 2023 at "Expert review of proteomics"
DOI: 10.1080/14789450.2023.2215440
Abstract: INTRODUCTION Investigating the taxonomic and functional composition of human microbiomes can aid in the understanding of disease etiologies, diagnosis, and therapy monitoring for several diseases, including inflammatory bowel disease or obesity. One method for microbiome…
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clinical use;
use metaproteomics;
advances clinical;
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Published in 2025 at "Personalized medicine"
DOI: 10.1080/17410541.2024.2447224
Abstract: Efforts have been made to leverage technology to accurately identify tumor characteristics and predict how each cancer patient may respond to medications. This involves collecting data from various sources such as genomic data, histological information,…
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cancer;
individualized medication;
advances clinical;
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Published in 2022 at "Asia-Pacific journal of ophthalmology"
DOI: 10.1097/apo.0000000000000584
Abstract: Many diseases that cause visual impairment, as well as systemic conditions, manifest in the posterior segment of the eye. With the advent of high-speed, high-resolution, reliable, and noninvasive imaging techniques, ophthalmologists are becoming more dependent…
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Keywords:
clinical applications;
imaging retinal;
advances clinical;
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Published in 2022 at "Current Opinion in Rheumatology"
DOI: 10.1097/bor.0000000000000872
Abstract: Purpose of review This review summarizes the recent literature exploring hydroxychloroquine levels and their relationship with disease activity and risk of toxicity. Recent findings There is no clear correlation between weight-based dosing of hydroxychloroquine and…
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rheumatology;
hydroxychloroquine levels;
advances clinical;
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Published in 2025 at "International journal of surgery"
DOI: 10.1097/js9.0000000000002518
Abstract: As pivotal mediators of intercellular communication, exosomes play a crucial role in transferring cellular cargo and regulating various biological functions. These extracellular vesicles encapsulate a diverse array of biomolecules, including nucleic acids, proteins, and lipids,…
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application exosomes;
clinical application;
advances clinical;
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Published in 2024 at "Current Opinion in Neurology"
DOI: 10.1097/wco.0000000000001246
Abstract: Purpose of review Clinical electroencephalography (EEG) is a conservative medical field. This explains likely the significant gap between clinical practice and new research developments. This narrative review discusses possible causes of this discrepancy and how…
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clinical electroencephalography;
field;
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Published in 2024 at "Gut"
DOI: 10.1136/gutjnl-2024-333565
Abstract: Many patients with IBD report persisting symptoms, despite resolution of the inflammatory process. Although by definition, a diagnosis of IBS cannot be made, the prevalence of ‘IBS in IBD’ surpasses the rate of IBS in…
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advances clinical;
ibs;
practice mastering;
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