Recent Advances and Clinical Applications of Exon Inclusion for Spinal Muscular Atrophy.
Sign Up to like & getrecommendations! Published in 2018 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-8651-4_3
Abstract: Spinal muscular atrophy (SMA) is an autosomal recessive disorder caused by a mutation in SMN1 that stops production of SMN (survival of motor neuron) protein. Insufficient levels of SMN results in the loss of motor… read more here.
Keywords: advances clinical; spinal muscular; recent advances; muscular atrophy ... See more keywords
Advances in the clinical translation of nanotechnology.
Sign Up to like & getrecommendations! Published in 2017 at "Current opinion in biotechnology"
DOI: 10.1016/j.copbio.2017.01.002
Abstract: The use of novel materials in the nano-scale size range for applications in devices, drugs and diagnostic agents comes with a number of new opportunities, and also serious challenges to human applications. The larger size… read more here.
Keywords: advances clinical; use; translation nanotechnology; pharmacology ... See more keywords
Recent advances in clinical development of leukotriene B4 pathway drugs.
Sign Up to like & getrecommendations! Published in 2017 at "Seminars in immunology"
DOI: 10.1016/j.smim.2017.08.007
Abstract: The LTB4 pathway is an attractive target for therapeutic drug development. Two broad classes of drugs have been pursued: antagonists of the primary LTB4 receptors (BLT1 and BLT2) and inhibitors of LTA4 Hydrolase (LTA4H), the… read more here.
Keywords: pathway drugs; advances clinical; pathway; recent advances ... See more keywords
Advances in the clinical use of metaproteomics.
Sign Up to like & getrecommendations! Published in 2023 at "Expert review of proteomics"
DOI: 10.1080/14789450.2023.2215440
Abstract: INTRODUCTION Investigating the taxonomic and functional composition of human microbiomes can aid in the understanding of disease etiologies, diagnosis, and therapy monitoring for several diseases, including inflammatory bowel disease or obesity. One method for microbiome… read more here.
Keywords: clinical use; use metaproteomics; advances clinical;
Recent Advances in Clinical Applications of Imaging in Retinal Diseases.
Sign Up to like & getrecommendations! Published in 2022 at "Asia-Pacific journal of ophthalmology"
DOI: 10.1097/apo.0000000000000584
Abstract: Many diseases that cause visual impairment, as well as systemic conditions, manifest in the posterior segment of the eye. With the advent of high-speed, high-resolution, reliable, and noninvasive imaging techniques, ophthalmologists are becoming more dependent… read more here.
Keywords: clinical applications; imaging retinal; advances clinical; applications imaging ... See more keywords
Advances in the clinical use of hydroxychloroquine levels
Sign Up to like & getrecommendations! Published in 2022 at "Current Opinion in Rheumatology"
DOI: 10.1097/bor.0000000000000872
Abstract: Purpose of review This review summarizes the recent literature exploring hydroxychloroquine levels and their relationship with disease activity and risk of toxicity. Recent findings There is no clear correlation between weight-based dosing of hydroxychloroquine and… read more here.
Keywords: rheumatology; hydroxychloroquine levels; advances clinical; use hydroxychloroquine ... See more keywords
Metabolic Reprogramming in Hematologic Malignancies: Advances and Clinical Perspectives
Sign Up to like & getrecommendations! Published in 2022 at "Cancer Research"
DOI: 10.1158/0008-5472.can-22-0917
Abstract: Abstract Metabolic reprogramming is a hallmark of cancer progression. Metabolic activity supports tumorigenesis and tumor progression, allowing cells to uptake essential nutrients from the environment and use the nutrients to maintain viability and support proliferation.… read more here.
Keywords: hematologic malignancies; clinical perspectives; advances clinical; metabolic reprogramming ... See more keywords
Recent Advances in Clinical Allergy and Immunology 2019
Sign Up to like & getrecommendations! Published in 2019 at "International Archives of Allergy and Immunology"
DOI: 10.1159/000504364
Abstract: The immune system has vital functions for homeostasis and host defense. Thus, imbalances of the immune system whether associated with allergy, hypersensitivity, or autoimmunity are of great importance, as is manifest from common diseases such… read more here.
Keywords: advances clinical; clinical allergy; allergy immunology; immunology 2019 ... See more keywords
Research advances and clinical management of bronchiectasis: Chinese perspective
Sign Up to like & getrecommendations! Published in 2022 at "ERJ Open Research"
DOI: 10.1183/23120541.00017-2022
Abstract: Bronchiectasis is a debilitating chronic suppurative airway disease that confers a substantial burden globally. Despite the notable prevalence, research on bronchiectasis in mainland China remains in its infancy. Nevertheless, there has been a significant leap… read more here.
Keywords: clinical management; advances clinical; bronchiectasis; research ... See more keywords
Advances in the clinical management of type 2 diabetes: a brief history of the past 15 years and challenges for the future
Sign Up to like & getrecommendations! Published in 2019 at "BMC Medicine"
DOI: 10.1186/s12916-019-1281-1
Abstract: Remarkable progress has been made in some aspects of diabetes care over the last 15 years, but there have also been a rising number of challenges that differ between high and low-income countries. In high-income… read more here.
Keywords: advances clinical; management type; clinical management; type diabetes ... See more keywords
Advances in clinical trial design for development of new TB treatments—Translating international tuberculosis treatment guidelines into national strategic plans: Experiences from Belarus, South Africa, and Vietnam
Sign Up to like & getrecommendations! Published in 2019 at "PLoS Medicine"
DOI: 10.1371/journal.pmed.1002896
Abstract: 1 Department of Tuberculosis, The International Union Against TB and Lung Disease, Geneva, Switzerland, 2 National Lung Hospital, Vietnam NTP, Vietnam, 3 Republican Scientific and Practical Centre for Pulmonology and TB, Minsk, Belarus, 4 Drug-Resistant… read more here.
Keywords: vietnam; clinical trial; south africa; advances clinical ... See more keywords