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Published in 2020 at "Medicinal research reviews"
DOI: 10.1002/med.21676
Abstract: Glioblastoma is the most aggressive primary brain tumor in adults. The prognosis of patients with primary glioblastoma treated with the current standard of care, tumor resection followed by radiation therapy and auxiliary temozolomide, remains poor.…
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drug development;
development targeted;
advances drug;
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Published in 2020 at "Current Medical Science"
DOI: 10.1007/s11596-020-2281-2
Abstract: Alzheimer’s disease (AD) is a chronic neurodegenerative disease that mainly causes dementia. It is a serious threat to the health of the global elderly population. Considerable money and effort has been invested in the development…
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advances drug;
drug therapy;
alzheimer disease;
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Published in 2017 at "European journal of medicinal chemistry"
DOI: 10.1016/j.ejmech.2017.08.070
Abstract: In the search of novel strategies for the treatment of cancer, photodynamic therapy (PDT) has emerged as an effective, safe for repeated use, and non-invasive method. This technique involves the use of two major non-toxic…
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Keywords:
drug discovery;
non porphyrinic;
recent advances;
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Published in 2017 at "Current drug metabolism"
DOI: 10.2174/1389200217666160921143616
Abstract: In clinical studies, drugs with hydrophobic characteristic usually reflect low bioavailability, poor drug absorption, and inability to achieve the therapeutic concentration in blood. The production of poor solubility drugs, in abundance, by pharmaceutical industries calls…
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advances drug;
drug delivery;
delivery polymeric;
drug ... See more keywords
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Published in 2018 at "Current drug targets"
DOI: 10.2174/1389450117666160401122926
Abstract: BACKGROUND Nanomedicine is currently exploited for manufacturing therapeutic DDS and treatments protocols for various diseases and disorders. To obtain DDS, different types of materials are used, from organic to inorganic, polar to non-polar, micro to…
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active agents;
advances drug;
drug delivery;
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Published in 2023 at "Current topics in medicinal chemistry"
DOI: 10.2174/156802662309230522141052
Abstract:
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Keywords:
drug discovery;
chemistry;
discovery parasitic;
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Published in 2023 at "Pharmaceuticals"
DOI: 10.3390/ph16040601
Abstract: Lysosomes are essential organelles of eukaryotic cells and are responsible for various cellular functions, including endocytic degradation, extracellular secretion, and signal transduction. There are dozens of proteins localized to the lysosomal membrane that control the…
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targeting lysosomal;
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Published in 2019 at "Future medicinal chemistry"
DOI: 10.4155/fmc-2018-0452
Abstract: Dendrimers are synthetic polymers that grow in three dimensions into well-defined structures. Their morphological appearance resembles a number of trees connected by a common point. Dendritic nanoparticles have been studied for a large number of…
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Keywords:
advances drug;
drug delivery;
delivery;
gene delivery ... See more keywords