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Published in 2022 at "Hormone research in paediatrics"
DOI: 10.1159/000524866
Abstract: BACKGROUND Type 1 diabetes (T1D) is a chronic autoimmune disease characterized by progressive destruction of the pancreatic beta-cells leading to a lifelong dependence on insulin. It is associated with an increased morbidity and mortality from…
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Keywords:
disease;
type diabetes;
advances immune;
beta cell ... See more keywords
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Published in 2017 at "Translational cancer research"
DOI: 10.21037/15193
Abstract: Immune checkpoint inhibitors (ICIs) have inaugurated a new era in the treatment of advanced malignancies. It is not only associated with higher progression-free survival and overall-survival but also a durable response that reached to 10…
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Keywords:
immune checkpoint;
advances immune;
would skyrocketed;
checkpoint inhibitors ... See more keywords
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Published in 2025 at "Frontiers in Oncology"
DOI: 10.3389/fonc.2025.1618903
Abstract: Immune checkpoint blockade (ICB), particularly targeting programmed cell death-1 (PD-1), has revolutionized cancer immunotherapy but remains limited by heterogeneous therapeutic responses and immune-related toxicities. This review systematically examines the integration of immune agonists—STING, TLR, CD40,…
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Keywords:
oncology;
advances immune;
immune agonists;
efficacy ... See more keywords