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Published in 2023 at "Advanced healthcare materials"
DOI: 10.1002/adhm.202203172
Abstract: Currently the demand for more reliable drug screening devices has made scientists and researchers develop novel potential approaches to offer an alternative to animal studies. Organ-on-chips are newly emerged platforms for drug screening and disease…
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Keywords:
drug screening;
organ chips;
advances organ;
drug ... See more keywords
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Published in 2018 at "Analytical Methods"
DOI: 10.1039/c8ay00970h
Abstract: In pharmaceutical research and development, improving the effectiveness of preclinical predictions is significant, thus in vitro and in vivo experimental models are needed to investigate human drug responses in organisms. As a microengineered model, an…
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Keywords:
analysis;
organ chip;
drug;
recent advances ... See more keywords
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Published in 2017 at "ANZ Journal of Surgery"
DOI: 10.1111/ans.13713
Abstract: Organ transplantation provides the best available therapy for a myriad of medical conditions, including endāstage renal disease, hepatic failure and type I diabetes mellitus. The current clinical reality is, however, that there is a significant…
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Keywords:
organ preservation;
transplantation;
preservation transplantation;
advances organ ... See more keywords
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Published in 2017 at "Science"
DOI: 10.1126/science.aao6334
Abstract: Inactivation of PERVs in the pig genome increases the safety of xenotransplantation Xenotransplantation, where tissue from one species is transplanted into a different species, is currently under development to help alleviate the increasing shortage of…
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Keywords:
organ transplant;
transplant pigs;
physiology;
xenotransplantation ... See more keywords