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Published in 2018 at "Drugs"
DOI: 10.1007/s40265-018-0865-y
Abstract: Migraine is a common and disabling neurological disorder, with a significant socioeconomic burden. Its pathophysiology involves abnormalities in complex neuronal networks, interacting at different levels of the central and peripheral nervous system, resulting in the…
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Keywords:
drugs recent;
advances pharmacotherapy;
pathophysiology;
recent advances ... See more keywords
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Published in 2021 at "Expert Opinion on Pharmacotherapy"
DOI: 10.1080/14656566.2021.1948011
Abstract: ABSTRACT Introduction: Head and neck squamous cell carcinoma (HNSCC) is one of the most common cancers worldwide and is a leading cause for cancer-related mortality. This review attempts to give a comprehensive summary of the…
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Keywords:
head;
neck cancer;
pharmacotherapy head;
advances pharmacotherapy ... See more keywords
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Published in 2022 at "Expert Opinion on Pharmacotherapy"
DOI: 10.1080/14656566.2022.2030704
Abstract: ABSTRACT Introduction The most common altered signaling found in aggressive iodine-refractory thyroid cancers derived from follicular cells (RAI-TC) are RTK, MAPK, PI3K, WNT, BRAF, RAS, RET, and TP53. Tyrosine Kinase Inhibitors (TKI) are multi-kinase inhibitors…
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Keywords:
advanced thyroid;
pharmacotherapy advanced;
thyroid;
origin ... See more keywords
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Published in 2022 at "Expert opinion on pharmacotherapy"
DOI: 10.1080/14656566.2022.2050214
Abstract: INTRODUCTION Acute kidney injury (AKI) is a clinically critical disease exhibiting an acute decline in renal function. The lack of an effective prevention and treatment method equates to a high morbidity and mortality rate. Consequently,…
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Keywords:
acute kidney;
advances pharmacotherapy;
pharmacotherapy acute;
kidney injury ... See more keywords
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Published in 2022 at "Expert Opinion on Pharmacotherapy"
DOI: 10.1080/14656566.2022.2054327
Abstract: ABSTRACT Introduction Aspirin or non-steroidal anti-inflammatory drugs (NSAIDs) and colchicine are first-line treatments for acute and recurrent pericarditis. Drugs blocking the NACHT, leucine-rich repeat, and pyrin domain-containing protein 3 (NLRP3) inflammasome/interleukin-1β (IL-1β) axis are beneficial…
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Keywords:
nlrp3 inflammasome;
acute recurrent;
pericarditis;
recurrent pericarditis ... See more keywords
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Published in 2022 at "Expert Opinion on Pharmacotherapy"
DOI: 10.1080/14656566.2022.2088281
Abstract: ABSTRACT Introduction Refractory migraine is associated with low quality of life and great socioeconomic burden. Despite high need for effective, tolerable preventive therapies, there has been little research on potential therapeutic options. Monoclonal antibodies (mAbs)…
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Keywords:
migraine;
pharmacotherapy prophylactic;
refractory migraine;
treatment ... See more keywords
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Published in 2023 at "Expert Opinion on Pharmacotherapy"
DOI: 10.1080/14656566.2023.2200931
Abstract: ABSTRACT Introduction Janus kinase (JAK) inhibitors are an emerging class of small-molecule drugs, providing targeted therapy for a variety of diseases, and have made their way into the treatment of armamentarium of ulcerative colitis (UC)…
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Keywords:
advances pharmacotherapy;
jak1 inhibitors;
jak inhibitors;
ulcerative colitis ... See more keywords
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Published in 2023 at "Expert Opinion on Pharmacotherapy"
DOI: 10.1080/14656566.2023.2210763
Abstract: ABSTRACT Introduction Bronchiectasis has become a growing concern of chronic airway disease because of the enormous socioeconomic burden. Four cardinal interdependent components – impaired airway defense, recurrent airway infections, inflammatory response, and airway damage, in…
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Keywords:
bronchiectasis;
pharmacotherapy bronchiectasis;
etiology;
bronchiectasis adults ... See more keywords
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Published in 2018 at "Current pharmaceutical design"
DOI: 10.2174/138161282414180713102806
Abstract:
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Keywords:
design;
advances pharmacotherapy;
drug design;
design inflammatory ... See more keywords