Advances in the Study of Hexokinase 2 (HK2) Inhibitors.
Sign Up to like & getrecommendations! Published in 2022 at "Anti-cancer agents in medicinal chemistry"
DOI: 10.2174/1871520623666221020092423
Abstract: Purpose The Warburg effect is an important metabolic feature of tumours, and hexokinase is the first rate-limiting enzyme of the glycolytic pathway during tumour metabolism. Among hexokinase subtypes, hexokinase 2 (HK2) is increasingly proving to… read more here.
Keywords: study hexokinase; advances study; hexokinase hk2; chemistry ... See more keywords
Advances in the study of nicotinamide adenine dinucleotide phosphate oxidase in myocardial remodeling
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Cardiovascular Medicine"
DOI: 10.3389/fcvm.2022.1000578
Abstract: Myocardial remodeling is a key pathophysiological basis of heart failure, which seriously threatens human health and causes a severe economic burden worldwide. During chronic stress, the heart undergoes myocardial remodeling, mainly manifested by cardiomyocyte hypertrophy,… read more here.
Keywords: nicotinamide adenine; heart failure; advances study; study nicotinamide ... See more keywords
Advances in the study of myeloid-derived suppressor cells in infectious lung diseases
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2023.1125737
Abstract: Myeloid-derived suppressor cells (MDSCs) are a heterogeneous population of immature cells capable of inhibiting T-cell responses. MDSCs have a crucial role in the regulation of the immune response of the body to pathogens, especially in… read more here.
Keywords: mdscs; myeloid derived; suppressor cells; advances study ... See more keywords
Advances in the study of axon–associated vesicles
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Molecular Neuroscience"
DOI: 10.3389/fnmol.2022.1045778
Abstract: The central nervous system is the most important and difficult to study system in the human body and is known for its complex functions, components, and mechanisms. Neurons are the basic cellular units realizing neural… read more here.
Keywords: advances study; axon associated; associated vesicles; pathology ... See more keywords
Advances in the Study of CircRNAs in Tumor Drug Resistance
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Oncology"
DOI: 10.3389/fonc.2022.868363
Abstract: Recent studies have revealed that circRNAs can affect tumor DNA damage and repair, apoptosis, proliferation, and invasion and influence the transport of intratumor substances by acting as miRNA sponges and transcriptional regulators and binding to… read more here.
Keywords: oncology; advances study; resistance; tumor ... See more keywords
Advances in the Study of circRNAs in Hematological Malignancies
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DOI: 10.3389/fonc.2022.900374
Abstract: Circular RNAs (circRNAs) are non–protein-coding RNAs that have a circular structure and do not possess a 5` cap or 3` poly-A tail. Their structure is more stable than that of linear RNAs, and they are… read more here.
Keywords: study circrnas; circrnas hematological; hematological malignancies; advances study ... See more keywords
Advances in the Study of the Ubiquitin-Editing Enzyme A20
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Pharmacology"
DOI: 10.3389/fphar.2022.845262
Abstract: Ubiquitin modification is a common post-translational protein modification and an important mechanism whereby the body regulates protein levels and functions. As a common enzyme associated with ubiquitin modification, the ubiquitin-editing enzyme A20 may be closely… read more here.
Keywords: editing enzyme; ubiquitin editing; advances study; study ubiquitin ... See more keywords