Advances in the TBAF-induced aldol-type addition of α-trialkylsilyl-α-diazoacetones: TIPS versus TES
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DOI: 10.1016/j.crci.2016.12.005
Abstract: Abstract α-Triisopropylsilyl-α-diazoacetone (TIPS-diazoacetone) underwent high-yielding “diazo-side” Mukaiyama aldol-type addition with a range of aryl and alkyl aldehydes when subjected to stoichiometric amount of tetrabutylammonium fluoride at −16 °C, in Et2O. Robustness of the TIPS group makes… read more here.
Keywords: type addition; tips diazoacetone; aldol type; advances tbaf ... See more keywords