Advances in therapeutic and vaccine targets for Cryptosporidium: challenges and possible mitigation strategies.
Sign Up to like & getrecommendations! Published in 2021 at "Acta tropica"
DOI: 10.1016/j.actatropica.2021.106273
Abstract: Cryptosporidium is known to be the second most common diarrheal pathogen in children, causing potentially fatal diarrhea and associated with long-term growth stunting and cognitive deficits. The only Food and Drug Administration-approved treatment for cryptosporidiosis… read more here.
Keywords: drug; advances therapeutic; targets cryptosporidium; vaccine targets ... See more keywords
Recent Advances in the Therapeutic Strategies of Glioblastoma Multiforme
Sign Up to like & getrecommendations! Published in 2022 at "Neuroscience"
DOI: 10.1016/j.neuroscience.2022.03.030
Abstract: Glioblastoma multiforme (GBM) is one of the most common, most formidable, and deadliest malignant types of primary astrocytoma with a poor prognosis. At present, the standard of care includes surgical tumor resection, followed by radiation… read more here.
Keywords: therapeutic strategies; treatment; advances therapeutic; recent advances ... See more keywords
Advances in the Therapeutic Application of Small-Molecule Inhibitors and Repurposed Drugs against Snakebite.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of medicinal chemistry"
DOI: 10.1021/acs.jmedchem.1c00266
Abstract: The World Health Organization has declared snakebite as a neglected tropical disease. Antivenom administration is the sole therapy against venomous snakebite; however, several limitations of this therapy reinforce the dire need for an alternative and/or… read more here.
Keywords: small molecule; advances therapeutic; repurposed drugs; therapeutic application ... See more keywords
Advances in therapeutic applications of extracellular vesicles
Sign Up to like & getrecommendations! Published in 2019 at "Science Translational Medicine"
DOI: 10.1126/scitranslmed.aav8521
Abstract: Understanding extracellular vesicle biology and production will pave the way for a new type of biotherapeutic. Extracellular vesicles (EVs) are nanometer-sized, lipid membrane–enclosed vesicles secreted by most, if not all, cells and contain lipids, proteins,… read more here.
Keywords: extracellular vesicles; medicine; applications extracellular; therapeutic applications ... See more keywords
Recent Advances in the Therapeutic Armamentarium of Acute Myeloid Leukemia: A Focus on the 63rd American Society of Hematology Annual Meeting Abstracts.
Sign Up to like & getrecommendations! Published in 2022 at "Current pharmaceutical design"
DOI: 10.2174/1381612828666220912092158
Abstract: read more here.
Keywords: armamentarium acute; therapeutic armamentarium; acute myeloid; advances therapeutic ... See more keywords
Advances in the therapeutic application and pharmacological properties of kinsenoside against inflammation and oxidative stress-induced disorders
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Pharmacology"
DOI: 10.3389/fphar.2022.1009550
Abstract: Extensive research has implicated inflammation and oxidative stress in the development of multiple diseases, such as diabetes, hepatitis, and arthritis. Kinsenoside (KD), a bioactive glycoside component extracted from the medicinal plant Anoectochilus roxburghii, has been… read more here.
Keywords: inflammation; oxidative stress; advances therapeutic; therapeutic application ... See more keywords
Advances on Therapeutic Strategies for Alzheimer’s Disease: From Medicinal Plant to Nanotechnology
Sign Up to like & getrecommendations! Published in 2022 at "Molecules"
DOI: 10.3390/molecules27154839
Abstract: Alzheimer’s disease (AD) is a chronic dysfunction of neurons in the brain leading to dementia. It is characterized by gradual mental failure, abnormal cognitive functioning, personality changes, diminished verbal fluency, and speech impairment. It is… read more here.
Keywords: therapeutic strategies; nanotechnology; clinical trials; alzheimer disease ... See more keywords
Recent Advances in the Therapeutic Efficacy of Artesunate
Sign Up to like & getrecommendations! Published in 2022 at "Pharmaceutics"
DOI: 10.3390/pharmaceutics14030504
Abstract: Artesunate, a semisynthetic artemisinin derivative, is well-known and used as the first-line drug for treating malaria. Apart from treating malaria, artesunate has also been found to have biological activity against a variety of cancers and… read more here.
Keywords: artesunate; advances therapeutic; efficacy artesunate; therapeutic efficacy ... See more keywords