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Published in 2021 at "Acta tropica"
DOI: 10.1016/j.actatropica.2021.106273
Abstract: Cryptosporidium is known to be the second most common diarrheal pathogen in children, causing potentially fatal diarrhea and associated with long-term growth stunting and cognitive deficits. The only Food and Drug Administration-approved treatment for cryptosporidiosis…
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Keywords:
drug;
advances therapeutic;
targets cryptosporidium;
vaccine targets ... See more keywords
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Published in 2022 at "Neuroscience"
DOI: 10.1016/j.neuroscience.2022.03.030
Abstract: Glioblastoma multiforme (GBM) is one of the most common, most formidable, and deadliest malignant types of primary astrocytoma with a poor prognosis. At present, the standard of care includes surgical tumor resection, followed by radiation…
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Keywords:
therapeutic strategies;
treatment;
advances therapeutic;
recent advances ... See more keywords
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Published in 2021 at "Journal of medicinal chemistry"
DOI: 10.1021/acs.jmedchem.1c00266
Abstract: The World Health Organization has declared snakebite as a neglected tropical disease. Antivenom administration is the sole therapy against venomous snakebite; however, several limitations of this therapy reinforce the dire need for an alternative and/or…
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Keywords:
small molecule;
advances therapeutic;
repurposed drugs;
therapeutic application ... See more keywords
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Published in 2019 at "Science Translational Medicine"
DOI: 10.1126/scitranslmed.aav8521
Abstract: Understanding extracellular vesicle biology and production will pave the way for a new type of biotherapeutic. Extracellular vesicles (EVs) are nanometer-sized, lipid membrane–enclosed vesicles secreted by most, if not all, cells and contain lipids, proteins,…
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Keywords:
extracellular vesicles;
medicine;
applications extracellular;
therapeutic applications ... See more keywords
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Published in 2022 at "Current pharmaceutical design"
DOI: 10.2174/1381612828666220912092158
Abstract:
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Keywords:
armamentarium acute;
therapeutic armamentarium;
acute myeloid;
advances therapeutic ... See more keywords
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Published in 2022 at "Frontiers in Pharmacology"
DOI: 10.3389/fphar.2022.1009550
Abstract: Extensive research has implicated inflammation and oxidative stress in the development of multiple diseases, such as diabetes, hepatitis, and arthritis. Kinsenoside (KD), a bioactive glycoside component extracted from the medicinal plant Anoectochilus roxburghii, has been…
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Keywords:
inflammation;
oxidative stress;
advances therapeutic;
therapeutic application ... See more keywords
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Published in 2022 at "Molecules"
DOI: 10.3390/molecules27154839
Abstract: Alzheimer’s disease (AD) is a chronic dysfunction of neurons in the brain leading to dementia. It is characterized by gradual mental failure, abnormal cognitive functioning, personality changes, diminished verbal fluency, and speech impairment. It is…
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Keywords:
therapeutic strategies;
nanotechnology;
clinical trials;
alzheimer disease ... See more keywords
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Published in 2022 at "Pharmaceutics"
DOI: 10.3390/pharmaceutics14030504
Abstract: Artesunate, a semisynthetic artemisinin derivative, is well-known and used as the first-line drug for treating malaria. Apart from treating malaria, artesunate has also been found to have biological activity against a variety of cancers and…
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Keywords:
artesunate;
advances therapeutic;
efficacy artesunate;
therapeutic efficacy ... See more keywords