Targeting HSP90 attenuates angiotensin II-induced adventitial remodeling via suppression of mitochondrial fission.
Sign Up to like & getrecommendations! Published in 2019 at "Cardiovascular research"
DOI: 10.1093/cvr/cvz194
Abstract: AIMS Adventitial remodeling presenting with the phenotypic switch of adventitial fibroblasts (AFs) to myofibroblasts (MFs) is reportedly involved in the evolution of several vascular diseases, including hypertension. In our previous study, we reported that heat… read more here.
Keywords: fission; mitochondrial fission; adventitial remodeling; hsp90 inhibition ... See more keywords